Results 131 to 140 of about 2,800 (290)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Strategic Joint Production Under Common-Pool Output Quotas: The Case of Fisheries Bycatch

open access: yes
We develop a simple game-theoretic model to explain the production decisions of firms when the production of a marketed good is complementary with the output of an associated good for which no market is available and the output of both goods is regulated
Abbott, Joshua K., Wilen, James E.
core  

Differences between demersal fisheries discards: high and low productivity zones of the Northwestern Mediterranean Sea [PDF]

open access: yes, 2012
Differences in fishery demersal discards in low and high productive marine ecosystems in the North-western Mediterranean were studied. Analyses were carried in three common fishing tactics carried out in different habitats from coastal to slope ...
Carbonell, A. (Ana)   +5 more
core  

Negative contribution of the fishing fleet to marine pollution

open access: yesRUDN Journal of Ecology and Life Safety
Operational waste, discharge of waste and biological resources overboard is an urgent issue of marine environment pollution. The modern fleet renewal program is more focused on modernization and contribution to deeper processing of products.
Andrei V. Iakimov
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Increasing the survival of discards in North Sea pulse-trawl fisheries

open access: yes, 2018
Measures to increase discard survival in the 80 mm pulse-trawl fisheries were assessed under commercial fishing conditions using plaice (Pleuronectes platessa) as model species.
Schram, Edward, Molenaar, Pieke
core   +1 more source

Drifting Nets as a Tool to Achieve Fish Management and Conservation Purposes in the Lower Danube River

open access: yesCroatian Journal of Fisheries
Drift trammel netting is a traditional method for commercial fish catches in the Danube River, especially along the Bulgarian stretch. Potentially, non-commercial or endangered fish species may be caught as bycatch, but no official statistics exist ...
Apostolos Apostolou, Boris Velkov
doaj   +1 more source

Improved detection of discarded fish species through BoxAL active learning

open access: yesCoRR
In recent years, powerful data-driven deep-learning techniques have been developed and applied for automated catch registration. However, these methods are dependent on the labelled data, which is time-consuming, labour-intensive, expensive to collect and need expert knowledge.
Maria Sokolova   +5 more
openaire   +2 more sources

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

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