Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Egyptian Journal of Aquatic Research, 2017 Vibriosis is a globally threatening bacterial disease affecting mariculture with high mortalities and severe economic losses. Isolation and Identification of different vibrio species were performed to a total number of one hundred moribund and freshly ...
Mohamed Abdelaziz +4 more
doaj +1 more source
Complete Genome Sequence of the Highly Virulent Aeromonas schubertii Strain WL1483, Isolated from Diseased Snakehead Fish ( Channa argus ) in China [PDF]
, 2016 Lihui Liu +6 more
openalex +1 more source
Evaluation of the activity of the immune system and age-related tissue markers in Turquoise killifish \ud (Nothobranchius furzeri, Jubb 1971) \ud and their role in cell ageing\ud [PDF]
, 2010 Currently the Turquoise Killifish is considered the best animal model suitable for aging research. \ud This annual fish, from south east Africa, shows an exceptionally adaptive behaviour to dry periods: indeed, due to this extreme environmental ...
Di Cicco, Emiliano, Rossi, Giacomo
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Frontiers in Veterinary ScienceEU Member States should ensure that they implement adequate health surveillance schemes in all aquaculture farming areas, as appropriate for the type of production.
Ana Muniesa +6 more
doaj +1 more source
Molecular epidemiology of helminth diseases of the humpback grouper, Cromileptes altivelis, as a pattern for mapping fish diseases in the Sunda Strait, Indonesia. [PDF]
Vet World, 2021 Subekti S +5 more
europepmc +1 more source
Texas Heart Institute Medal and the Ray C. Fish Award for Scientific Achievement in Cardiovascular Diseases [PDF]
, 2017 James T. Willerson
openalex +1 more source
Lethal Parasites in Oysters from Coastal Georgia with Discussion of Disease and Management Implications [PDF]
, 1992 Extensive mortalities of oysters, Crassostrea virginica, occurred from 1985 through 1987 in coastal waters of Georgia. Fluid thioglycolate cultures of oysters collected from 16 of 17 locations revealed infections by the apicomplexan parasite Perkinsus ...
Heffernan, Peter B. +5 more
core
An overview of diseases in fish hatcheries and nurseries.
, 2017 Academic Editor: Tanvir Rahman Quality and healthy fish seed is the prerequisite for sustainable aquaculture. A major challenge to the expansion of aquaculture production is the outbreak of diseases.
M. A. R. Faruk, Ishrat Z. Anka
semanticscholar +1 more source