Results 61 to 70 of about 122,389 (256)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Assessment of fish fauna in relation to biodiversity indices of Chalan Beel, Bangladesh
International Journal of Aquatic Biology, 2016 The research was carried out to enlist the fish species diversity along with diversity indices of existing fish species of Chalan Beel, Bangladesh. During the study, a total of 78 fish species including 69 native and 9 exotic fish species were recorded ...
Md. Abu Bakar Siddique +3 more
doaj
Evolutionary ApplicationsReliable estimates of population abundance and demographics are essential for managing harvested species. Ice‐associated phocids, “ice seals,” are a vital resource for subsistence‐dependent coastal Native communities in western and northern Alaska, USA ...
Brian D. Taras +7 more
doaj +1 more source
Journal of Threatened TaxaFish diversity in relation to macrophyte distribution and physicochemical parameters was studied across six wetlands in Vellore District, Tamil Nadu, India.
Annie Pushpa Isaac +3 more
doaj +1 more source
, 2017 Habitat is the place where a species lives and its surrounding biotic and abiotic environment. Ecologists seeking to develop explanatory and forecast models have long wondered about this fundamental question: how can the presence of an individual at a given place and time be explained? Indeed, the different fish species are not distributed at random in
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Acta Scientiarum: Biological Sciences, 2018 The degradation of riparian vegetation in low-order streams can cause irreversible environmental damage, biodiversity loss and alter the structure of communities.
Lucena Rocha Virgilio +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FishesHydrological changes caused by dam construction are among the primary drivers of global freshwater biodiversity decline. To assess the current status of fish community diversity and examine the impacts of cascade hydropower development on fish diversity,
Jiaming Zhang +6 more
doaj +1 more source