Results 71 to 80 of about 1,536,362 (374)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Gas Chromatography–Mass Spectrometry-Based Metabolite Profiling for the Assessment of Freshness in Gilthead Sea Bream (Sparus aurata)

open access: yesFoods, 2020
Gilthead sea bream (Sparus aurata) is one of the most important farmed Mediterranean fish species, and there is considerable interest for the development of suitable methods to assess its freshness.
Athanasios Mallouchos   +2 more
doaj   +1 more source

Fresh Fish: Observation up Close in Late Seventeenth-Century England [PDF]

open access: yesNotes and Records: the Royal Society Journal of the History of Science, 2020
The traditional view of London's Royal Society as a closed circle has been subject to revision in the past decades. Historians have shown the considerable extent to which the Fellows of the Society drew on a broad range of men of practice for their respective skill sets.
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Factors affecting the rheological properties of gels made from hoki (Macruronus novaezelandiae) : a thesis presented in partial fulfillment of the requirements for the degree of Master of Technology at Massey University / [PDF]

open access: yes, 1989
Hoki (Macruronus novaezelandiae) is an important commercial fish in the New Zealand Exclusive Economic Zone. The resource remains underutilized with only a small proportion of the 250,000 tonnes Total Allowable Catch presently being made into added value
MacDonald, Grant Arthur
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A profile of the Australian seafood consumer [PDF]

open access: yes, 2013
Seafood is an important food industry globally and increasing seafood consumption is high on the agenda of many developed countries.Understanding consumers is fundamental to the development of any marketing strategy, and while considerable research has ...
Birch, Dawn, Lawley, M
core  

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