Results 51 to 60 of about 3,866,602 (280)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Fish Commission research briefs. Vol. 2, no. 1

open access: yes
These short reports are intended to inform the public, industry, and other interested parties of the current studies of the Commission's staff and the basis for conservation measures.
Oregon. Fish Commission
core   +4 more sources

Development of 3D printed fish product enriched with marine polyunsaturated fatty acids

open access: yesScientific Reports
3D printing is the latest novel technology for developing complex food and other non-food items in an easy way. Engineered food products are gaining increased importance due to the advantages it offers like refinement of food textures, tailoring the ...
Meembidi Rasheeda   +6 more
doaj   +1 more source

Effect of ellagitannin metabolites ellagic acid and urolithins A-D on the non-enzymatic glycation of human serum albumin and inhibiting mechanisms

open access: yesFood Science and Human Wellness
Effect of ellagitannins gut microbiota metabolites ellagic acid (EA) and urolithin A-urolithin D (UroA-UroD) on human serum albumin (HSA) glycation were firstly evaluated in this research. The inhibition mechanisms were investigated by methylglyoxal (MGO)
Chunyan Peng   +7 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Improving foaming properties of fish gelatin by neutral protease and gum arabic

open access: yesnpj Science of Food
Neutral protease and gum arabic (GA) were combined to enhance foaming ability (FA) and foaming stability (FS) of fish gelatin. Meanwhile, structural changes of pure, single-modified and combined-modified fish gelatins were evaluated in detail to ...
Yu Chen   +6 more
doaj   +1 more source

Preparation and Standardization of Shrimp Head Masala Powder from Parapenaeopsis stylifera Head

open access: yesInternational Journal of Bio-Resource and Stress Management
Freshly separated Shrimp heads of P. Stylifera (Kiddi Shrimp) were procured from peeling sheds during the period of January to April, 2024 near Mirkarwada Landing center, Taluka-Ratnagiri District-Ratnagiri, Maharashtra, India aimed at the development ...
D. R. Bhaladhare   +9 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Effects of Different Reducing Sugars on the Structure and Allergenicity of Silver Carp Parvalbumin via Noncovalent Interaction

open access: yesShipin gongye ke-ji
Taking parvalbumin (PV) from silver carp as the research object, four different reducing sugars-glucose, ribose, maltose and maltotriose, were selected to noncovalently with PV.
Jie LIU   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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