Results 101 to 110 of about 229,943 (264)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Microplastic pollution in aquafeed of diverse aquaculture animals
HeliyonMicroplastics have emerged as pervasive contaminants, and determining their occurrence in aquafeed is key for evaluating their risks to farmed animals and, by extension, humans. However, knowledge about microplastic in aquafeed is still limited.
Mohamed Mohsen +4 more
doaj +1 more source
Habitat quality and fish population [PDF]
, 2016 Degradation of marine ecosystem due to, among others, eutrophication and climate change, has been of concern for sustainable fishery management worldwide, but studies on associated impacts on fish populations are rare. The purpose of this study is to estimate effects of nutrient loads, which cause eutrophication, on the perch population at the Swedish ...
Tafesse Tirkaso, Wondmagegn +1 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Assessment and Monitoring of Fish Quality from a Coastal Ecosystem under High Anthropic Pressure: A Case Study in Southern Italy. [PDF]
Int J Environ Res Public Health, 2020 La Torre GL +9 more
europepmc +1 more source
Improving the quality control of fish and fish products
, 2020 We examined veterinary-sanitary tests of fish and fish products by organoleptic, chemical, bacteriological and histological methods of product freshness. The histamine increased in safety process in comparative to un normal technology of safety and fish processing.
openaire +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
ON THE QUALITY OF FISH PRODUCTS
GISAP:Biology, Veterinary Medicine and Agricultural Sciences, 2016 Galina Khimich, Rustam Gasymov
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