Results 81 to 90 of about 177,321 (314)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Effect of different types of base solution on physico-chemical characteristics of Eucheuma cottonii carrageenan flour [PDF]
BIO Web of ConferencesEucheuma cottonii is red seaweed (Rhodophyceae) producing carrageenan which is widely cultivated to be utilized for its products, one of which is the basic material for making edible films.
Sirait Putriana Sari +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Use of Magnetic Technology to Grow the Duckweed Lemna sp. Plant and Invest its Live Mass in Feeding Fish [PDF]
, 2023 Nidhal Tahseen Taha Al-Taee +1 more
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
A New Approach for the Utilization of Technical Egg Albumen Based on Acid–Thermal Coagulation
Applied SciencesTechnical albumen (TA) is liquid waste from egg processing enterprises and occupies a share of 10–15% of the waste. Proteins have the property at the isoelectric point of weakening their repulsive forces.
Plamen Saraliev +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Metabolomics-based strategies for fish meat quality, authentication and food safety: a review
Food, Nutrition and HealthFish meat is well known for having exceptional nutritional profile, full of omega-3 fatty acids and essential amino acids which contribute to human health and disease prevention.
Pallavi Bhalavey +13 more
doaj +1 more source