Results 51 to 60 of about 1,654,556 (276)
Farmed fish welfare research status in Latin America: A review [PDF]
Latin America (LATAM) plays an important role in the world's production of aquatic animals and is the second most productive region in the world. Chile, Ecuador, Brazil, Mexico, Colombia, and Perú contribute 87% of LATAM aquaculture production.
Ruiz-Gómez, María de Lourdes +6 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Social behaviors as welfare indicators in teleost fish
Frontiers in Veterinary Science, 2023 Animal welfare is a key issue not only for aquaculture industry and food production, but also for daily husbandry practices in research topics related to physiology in wild and farmed animals.
Luciano Cavallino +5 more
doaj +1 more source
Assessing economic and welfare values of fish in the Lower Mekong Basin; Welfare Component
, 2019 As part of the project “Assessing economic and welfare values of fisheries in the Lower Mekong Basin” a large fish focused household welfare survey was initiated in 2012 by WorldFish and ...
Freed, Sarah
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Effects of structural environmental enrichment on welfare of juvenile seabream (Sparus aurata)
Aquaculture Reports, 2019 Current production systems of finfish aquaculture, and in particular intensive farming systems, can cause welfare problems leading not only to poor condition of the fish but also to a decrease in product quality.
P. Arechavala-Lopez +8 more
doaj +1 more source
Risk assessment in fish welfare, applications and limitations
, 2011 The Treaty of Amsterdam, in force since 1 May 1999, has established new ground rules for the actions of the European Union (EU) on animal welfare. It recognizes that animals are sentient beings and obliges the European Institutions to pay full regard to ...
Müller-Graf, C. +9 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Animal Welfare Issues in Capture-Based Aquaculture
Animals, 2021 Capture-based aquaculture (CBA) represents a type of intensive aquaculture production system for some economically valuable fish species, such as bluefin tuna (Thunnus thynnus), eel (Anguilla spp.) and Atlantic cod (Gadus morhua).
Uthpala Chandararathna +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source