Results 81 to 90 of about 1,654,556 (276)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Stunning fish with CO2 or electricity: contradictory results on behavioural and physiological stress responses

open access: yesAnimal, 2016
Studies that address fish welfare before slaughter have concluded that many of the traditional systems used to stun fish including CO2 narcosis are unacceptable as they cause avoidable stress before death.
A. Gräns   +9 more
doaj   +1 more source

National fish, wildlife and plants climate adaptation strategy

open access: yes, 2013
The purpose of the National Fish, Wildlife and Plants Climate Adaptation Strategy is to inspire and enable natural resource administrators, elected officials, and other decision makers to take action to adapt to a changing climate.
National Fish, Wildlife and Plants Climate adaptation Partnership
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Ethics and the Welfare of Fish

open access: yes, 2020
To what extent fish can experience suffering and enjoyment is not just an empirical question, but one that also calls for ethical reflection. This is firstly, because animal welfare research is value laden and secondly, because the empirical evidence requires a normative framework in order to become action guiding in practices involving fish, such as ...
Bovenkerk, B., Meijboom, Franck
openaire   +3 more sources

Fish welfare: the state of science by scientometrical analysis

open access: yesActa Scientiarum: Biological Sciences, 2016
  In 2014, Brazil produced 474.33 thousand tons of captive-bred fish. In addition, regulatory agencies of animal ethics and welfare have recently encouraged experiments to be done using simpler vertebrates, such as fish.
Nédia de Castilhos Ghisi   +1 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Celebrating the Wildlife and Sport Fish Restoration program: 75 years of conservation and partnership success

open access: yes, 2013
Seventy-five years of successful wildlife management is the remarkable legacy of the Pittman-Robertson Wildlife Restoration Act, and the cause of our 75th celebration. Along with the Dingell-Johnson Sport Fish Restoration Act, it is the foundation of the
U.S. Fish and Wildlife Service
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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