Results 101 to 110 of about 747,762 (279)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Common stationary points of multivalued mappings on bounded metric spaces
International Journal of Mathematics and Mathematical Sciences, 2000 Necessary and sufficient conditions for the existence of common stationary points of two multivalued mappings and common stationary point theorems for multivalued mappings on bounded metric spaces are given.
Zeqing Liu, Shin Min Kang
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Information Geometry on the \(\kappa\)-Thermostatistics
Entropy, 2015 We explore the information geometric structure of the statistical manifold generated by the \(\kappa\)-deformed exponential family. The dually-flat manifold is obtained as a dualistic Hessian structure by introducing suitable generalization of the Fisher
Tatsuaki Wada, Antonio M. Scarfone
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
George Fisher at the Drawing Board Searching for Cartoon Ideas
, 1995 Cartoon by Fisher of a cartoonist holding his head in his hands and surrounded by cartoon images of well-known political figures. Woman's text bubble on recto: "No idea for a cartoon?
Fisher, George, 1923-2003
core +1 more source
Improving Flat Maxima with Natural Gradient for Better Adversarial Transferability
Big Data and Cognitive ComputingDeep neural networks are vulnerable and susceptible to adversarial examples, which can induce erroneous predictions by injecting imperceptible perturbations.
Yunfei Long, Huosheng Xu
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Common Fixed Point Theorem in Metric Spaces of Fisher and Sessa
Journal of Mathematical Extension, 2015 In this paper it is shown that T and I have a unique common fixed point on a compact subset C of a metric space X, where T and I are two self maps on C, I is non-expansive and the pair (T, I) is weakly commuting.
A. R. Valipour Baboli, M. B. Ghaemi∗
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