Results 121 to 130 of about 747,762 (279)
The Roy B. Fisher, D.O. Collection
, 1998 Finding aid for the Roy B. Fisher, D.O. CollectionRoy Benjamin Fisher, D.O. (1910-1998), was a prominent physician in Fort Worth, Texas and one of founders of the Fort Worth Osteopathic Hospital (later the Osteopathic Medical Center of Texas).
Fisher, Roy B.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
A general unique common fixed point theorem for hybrid pairs of mappings in metric spaces [PDF]
Surveys in Mathematics and its Applications, 2016 The purpose of this paper is to prove a general unique common fixed point theorem for two pairs of mappings using Hausdorff - Pompeiu metric, which generalizes, in a correct form, the results from [H. Bouhadjera, A. Djoudi and B.
Valeriu Popa, Alina-Mihaela Patriciu
doaj
Extending the Fisher metric to density matrices
, 2001 Latex file, written version of a conference talk at Aarhus ...
Petz, D., Sudar, Cs.
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Envelope with Artwork for a Letter from Fisher to His Wife, Rosemary
, 1950 Envelope with art work for a letter from Fisher to his wife. In addition to the recipient's name and address, there is an image of a barefoot hillbilly character delivering letters and gifts in a one-wheeled wooden cart to the addressee, Mrs.
Fisher, George, 1923-2003
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