Results 191 to 200 of about 835,199 (355)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
From Genes to Fisheries: A Synthesis of Current Research in Crustacean Biology and Management. [PDF]
Biology (Basel)Duan Y, Auerswald L, Meng X.
europepmc +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
FEBS Open Bio, EarlyView.Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski +13 more
wiley +1 more source
Out of Sight, out of Mind? Evidence of Human-Induced Threats in the Elusive <i>Ziphius cavirostris</i> of the Mediterranean Sea. [PDF]
Ecol EvolGazo M +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
Ecological legacy of Indigenous dispossession: disruption of ancestral sea gardens by commercial clam fisheries in British Columbia, 1882-1985. [PDF]
Philos Trans R Soc Lond B Biol SciHayes P +3 more
europepmc +1 more source