Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Multi-output distance function for the North Sea Beam Trawl Fishery [PDF]
, 2002 Interactions between species in a fishery may be either biological (e.g. predatorprey) or technical (e.g. joint production). Technical interactions within fisheries have generally been assumed to exist, although the strength of these interactions has ...
Bjorndal, T., Koundouri, P., Pascoe, S.
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Impacts of Novel Coronavirus (COVID-19) Pandemic on Fisheries Sector in India: A Minireview
, 2020 Soumyadip Purkait
openalex +1 more source
Discards from the commercial gillnet fishery for dusky flathead, Platycephalus fuscus, in New South Wales, Australia: spatial variability and initial effects of change in minimum legal length of target species [PDF]
, 2004 Charles A. Gray +3 more
openalex +1 more source
Recent Developments in Fisheries Science and Their Prospects for Improving Fisheries Contributions to Food Security [PDF]
, 2011 Marine reserves, areas permanently closed to all fishing, are frequently proposed as a tool for managing fisheries. Fishery benefits claimed for reserves include increases in spawning stock size, animal body size, and reproductive output of exploited ...
Callum M. Roberts, Fiona R. Gell
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Using stock assessment information to assess fishing capacity of tuna fisheries [PDF]
, 2009 Haritz Arrizabalaga +3 more
openalex +1 more source
Guide to fisheries policy research in Cambodia : the institutional and legal context [PDF]
Fishery policy, Fishery management, Legal aspects, Cambodia,
Ahmed, M. +3 more
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