Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
A bio-economic model for the ecosystem-based management of the coastal fishery in French Guiana [PDF]
This paper offers a theoretical and empirical modeling for ecosystem-based fishery management (EBFM). A multi-species and multi-fleets model integrating Lokta-Volterra trophic dynamics and profit functions is developed for the coastal fishery of French ...
Abdoul CISSE (IFREMER-Guyane et CEREGMIA, UAG) +4 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Strategic Priorities of Shipbuilding of a Fishery Complex of Russia
Управленческое консультирование, 2018 In the article tendencies of a condition of fleet of a fishery complex during the Post-Soviet period are considered and prerequisites for formation of measures of the state support of development of branch are analyzed.
Andrey Alfredovich Beletskiy
doaj
Fisheries Biology of the Tanner Crab, Chionoecetes opilio-I
, 1967 Tohshi KON
openalex +2 more sources
Research progress of anti-fouling materials for fishing and its application in fisheries [PDF]
, 2021 Yue Wang +6 more
openalex +1 more source
How can Fishery Comanagement Groups Enhance Economic Performance? Hints from Japanese Coastal Fisheries Management [PDF]
Although comanagement is gaining increasing attention as a way to manage fisheries, few studies have attempted to understand quantitatively which factors of comanagement are critical for their success. This study investigates fishery comanagement regimes
Uchida, Hirotsugu, Wilen, James E.
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Fisheries in a border area of the Moxos Lowlands (Bolivia) after invasion of Arapaima gigas [PDF]
, 2023 Gabriela Rico Lopez +4 more
openalex +1 more source
Cost-Benefit Analysis of the Greenland Offshore Shrimp Fishery [PDF]
This paper examines the social economic value of the Greenland off-shore shrimp fishery. The contribution of the fishery to the economy is examined us-ing a cost-benefit analysis where the objective of the report is to examine the current state of the ...
Claas Wagner +2 more
core +1 more source