Results 91 to 100 of about 439,875 (265)

Caribbean coral reef fishery resources [PDF]

open access: yes
Reef fisheries, Coral reefs, Fishery management, Fishery biology, Fishery resources, Reef fish, Caribbean,
Munro, J.L. (ed.)
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Bioeconomics of the Philippine small pelagics fishery [PDF]

open access: yes
Time series analysis of catch and effort data in the Philippines small pelagics fishery resulted in a level of biological and economic overexploitation.
Corpuz, P.V.   +3 more
core  

Discard sampling of the Dutch Nephrops fishery in 2007-2008 [PDF]

open access: yes, 2009
Dit rapport bevat de resultaten van een bemonsteringsprogramme van discards (DCR programma) in de Nederlandse visserij op Noorse kreeft in de Noordzee in 2007 en 2008.
Helmond, A.T.M., van   +3 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Dynamics of an Open-access Fishery: Baltic Sea Cod [PDF]

open access: yes
This paper sets up a dynamic open-access model of a single industry exploiting a single resource stock. The model is applied empirically to describe the dynamics of the eastern Baltic Sea cod fishery.
Kronbak, Lone Gronbaek
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Results of economic usage of the pacific salmon resources in the Sakhalin-Kuril region in 2023

open access: yesИзвестия ТИНРО
Pacific salmon fishery in the Sakhalin-Kuril region in 2023 is considered. The landing of 78.2.103 t was forecasted but the actual annual catch was 75.8.103 t or 97 % of the forecast. This ratio was the following for the mass species: pink salmon — 34643
A. A. Makoedov   +5 more
doaj   +1 more source

ANALYZING TECHNICAL AND ECONOMIC INTERRELATIONSHIPS IN HAWAII'S LONGLINE FISHERY [PDF]

open access: yes
This paper provides an analysis of technical and economic interrelationships among species harvested in Hawaii's pelagic longline fishery. The results indicate that this multispecies fishery is characterized by a joint production process, meaning that ...
Leung, PingSun   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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