Results 101 to 110 of about 1,700 (296)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A Bioeconomic Analysis of the Greenland Shrimp Fishery in the Davis Strait

open access: yes
This paper presents a bioeconomic analysis determining the resource rent and optimum effort of the shrimp (Pandalus borealis) fishery in the Davis Strait, taking into account the discard behaviour of the fleet.
Christensen, Steen, Vestergaard, Niels
core  

Extracting spatial patterns of ocean fishery using GIS and RS - Taking the East China Sea as an example

open access: yes, 2003
The ocean fishery and the corresponding environment are highly interrelated according to the production experiences of ocean fishing population. The spatial cluster patterns are constructed using the remote sensed data and long-time series fishery ...
Zhou C. H.   +4 more
core  

Key features and context-dependence of fishery-induced trophic cascades.

open access: yes, 2010
Trophic cascades triggered by fishing have profound implications for marine ecosystems and the socioeconomic systems that depend on them. With the number of reported cases quickly growing, key features and commonalities have emerged.
Gaines, SD   +5 more
core   +1 more source

FORECASTING FRESH WATER AND MARINE FISH PRODUCTION IN MALAYSIA USING ARIMA AND ARFIMA MODELS

open access: yesMalaysian Journal of Computing, 2018
Malaysia is surrounded by sea, rivers and lakes which provide natural sources of fish for human consumption. Hence, fish is one source of protein supply to the country and fishery is a sub-sector that contribute to the national gross domestic product ...
P.J.W. Mah, N.N.M. Zali, N.A.M. Ihwal, N.Z. Azizan
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Bioeconomic Analysis of the Northwestern Hawaiian Islands Lobster Fishery

open access: yes
Several surplus production-based bioeconomic models are applied to the Northwestern Hawaiian Islands (NWHI) commercial lobster fishery. The model which best explains the biological dynamics of the fishery is a modification of the Fox model developed by ...
Clarke, Raymond P.   +2 more
core  

Forecasting models for tuna fishery with aerospatial remote sensing

open access: yesInternational Journal of Remote Sensing, 1991
Abstract Tropical tuna movements can be observed from space. We must deduce them by models based on tuna behaviour. To find high concentrations of tunas, we have to find areas with high density of tuna forage. The knowledge of the surface thermal signature of fertilizing processes of water masses is possible using satellite infrared radiometers. We can
openaire   +2 more sources

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