Results 101 to 110 of about 439,875 (265)

Assessment of demersal fishery resources in Brunei Darussalam [PDF]

A problem commonly encountered in stock assessments of tropical marine resources in developing countries is data paucity, which invariably results from the lack of both human and economic capacity within the government to implement and maintain ...
Ebil, Syazana
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Socioeconomics of Individual Transferable Quotas and Community-Based Fishery Management [PDF]

In many fisheries around the world, the failures of centralized, top-down management have produced a shift toward co-management—collaboration and sharing of decision making between government and stakeholders.
Copes, Parzival, Charles, Anthony T.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Cost-Benefit Analysis of the Greenland Offshore Shrimp Fishery [PDF]

This paper examines the social economic value of the Greenland off-shore shrimp fishery. The contribution of the fishery to the economy is examined us-ing a cost-benefit analysis where the objective of the report is to examine the current state of the ...
Claas Wagner, Kristiana A. Stoyanova, Niels Vestergaard   +2 more
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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

FORECASTING FRESH WATER AND MARINE FISH PRODUCTION IN MALAYSIA USING ARIMA AND ARFIMA MODELS

Malaysian Journal of Computing, 2018
Malaysia is surrounded by sea, rivers and lakes which provide natural sources of fish for human consumption. Hence, fish is one source of protein supply to the country and fishery is a sub-sector that contribute to the national gross domestic product ...
P.J.W. Mah, N.N.M. Zali, N.A.M. Ihwal, N.Z. Azizan
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Pink salmon fishery in the Far-Eastern fishing basin in 2025: results of the season, analysis of deviations, reliability of the forecast

Известия ТИНРО
Results of the pink salmon (Oncorhynchus gorbuscha) fishery season in the Russian Far East in 2025 (odd-year brood line) are analyzed on data of fishery statistics and marine trawl surveys conducted in 2024 – 2025.
A. A. Somov, E. A. Shevlyakov, A. N. Starovoitov, V. A. Shevlyakov, S. V. Naydenko, N. A. Dederer, A. N. Kanzeparova, I. V. Melnikov   +7 more
doaj   +1 more source

How can Fishery Comanagement Groups Enhance Economic Performance? Hints from Japanese Coastal Fisheries Management [PDF]

Although comanagement is gaining increasing attention as a way to manage fisheries, few studies have attempted to understand quantitatively which factors of comanagement are critical for their success. This study investigates fishery comanagement regimes
Wilen, James E., Uchida, Hirotsugu
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