Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
E-educational Resource for Simulator Training of Marine Engineers and Bachelors in Engineering
Sustainable development of the Baltic Sea region cannot be imagined without the continuous improvement of the quality of higher education. Maritime and ecological education takes a special role in the development of this region. Shipping has always had a
Mikhail Nikishin +2 more
doaj
Species Trends in Sport Fisheries, Monterey Bay, Calif., 1959-86 [PDF]
Three surveys spanning 28 years were examined for changes in species caught by recreational fishermen from small boats (skiffs) and commercial passenger fishing vessels (CPFV's) in California's Monterey Bay region.
Mason, Janet E.
core
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Mathematical substantiation of parameters of safe pelagic trawling in the canyon [PDF]
The authors have offered and proved the following security options of pelagic trawling in the sea canyon: the tolerance of the vessel from the optimal track; the minimum width of the canyon giving opportunity for the conditions to ensure the safety of ...
Danilov Yu. A., Ermakov S. V.
doaj
Catch Shares in Action: Samoan Safata District Customary User Rights Program [PDF]
The Samoan Customary User Rights System is an area-based catch share program that formalizes the customary fishing rights of native communities. Authorized by legislative reforms, fishing communities voluntarily establish and manage Territorial Use ...
Jeff Young
core
Hog Daddy and the Walls of Steel: Catch Shares and Ecosystem Change in the New England Groundfishery [PDF]
The U.S. National Oceanic and Atmospheric Administration implemented marketbased fishery management in the New England groundfishery as catch shares, controlling aggregate harvests through tradable annual catch quotas allocated to fishing groups called ...
Brewer, Jennifer F
core +2 more sources
Response of benthic fauna to experimental bottom fishing: A global meta‐analysis
Bottom‐contact fishing gears are globally the most widespread anthropogenic sources of direct disturbance to the seabed and associated biota. Managing these fishing disturbances requires quantification of gear impacts on biota and the rate of recovery ...
M. Sciberras +16 more
semanticscholar +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Strategic Study for Sustainable Development of Freshwater Aquaculture in Camagüey
A strategic study of biological-fishing behavior of the main variables determined for extensive freshwater aquaculture was made in facilities of the Camagüey Fishing Company, province of Camagüey, Cuba.
Pedro Enrique Ramírez Fernández +2 more
doaj

