Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen +10 more
wiley +1 more source
Metals and Geochemical Indexes in Sediments of a Karstic Coastal Tropical Lagoon: Evaluating the Ecological Risk in Celestun, Yucatan, Mexico. [PDF]
Arcega-Cabrera F +3 more
europepmc +1 more source
Investigation of an outbreak of acute algal-associated dermatoses among artisanal fishermen in Senegal: A one health approach. [PDF]
Ndiaye M +10 more
europepmc +1 more source
Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang +11 more
wiley +1 more source
Commercial fishing amplifies impacts of increasing temperature on predator-prey interactions in marine ecosystems. [PDF]
Shurety AL +4 more
europepmc +1 more source
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley +1 more source
Reestablishment and Conservation Implications of the Milu Deer Population in Poyang Lake. [PDF]
Cheng Z +10 more
europepmc +1 more source
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza +2 more
wiley +1 more source
Strengthening community-based fisheries monitoring programs with Indigenous perspectives. [PDF]
Dewan K, Mulrennan ME, Georgekish E.
europepmc +1 more source
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac +2 more
wiley +1 more source

