Results 51 to 60 of about 25,649 (133)

A Selective Cortico‐Limbic Network Organizes Behavior During Reward Seeking Under Threat

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
In the SDAmC task, rats step down from safety and cross a threat‐associated context for saccharin. PL limits approach, pIC supports risk assessment, BLA supports avoidance across motivational states, and NAc supports goal‐directed behavior under conflict; IL, lOFC, aIC, and LHb showed no detectable effects.
Rodrigo O. Sierra, Leticia Ramirez‐Lugo, Elizabeth Illescas‐Huerta, Axel R. Bolaños, Francisco Sotres‐Bayon   +4 more
wiley   +1 more source

Malassezia: Estado del conocimiento y perspectivas en su estudio Malassezia: Current knowledge and study perspectives

Revista Argentina de Microbiología, 2006
El estudio del género Malassezia se mantuvo postergado durante años debido a sus estrictos requerimientos nutricionales y su variabilidad morfológica.
Gustavo E. Giusiano
doaj  

Editorial Volumen 1 Nro. 2 (2016)

Revista Científica Arbitrada de la Fundación MenteClara, 2016
Les doy la bienvenida a este segundo número. Un excelente equilibrio entre fisiología, política y religión; con artículos atravesados por, o que cuestionan, la visión tántrica de sujeto. Los cuatro trabajos seleccionados sintetizan el espíritu presentado
Oscar R. Gómez
doaj   +1 more source

Progerin Hinders Autophagy Flux at Its Final Stages in Hutchinson‐Gilford Progeria Syndrome Cells, Preventing Its Own Autophagic Degradation

Aging Cell, Volume 25, Issue 8, August 2026.
We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre, Jesús Alejandro Reyes‐Martínez, Juan Unzueta, Francisco Guevara‐Namorado, Solangy Lizcano‐Meneses, Susana Gonzalo, Angel Baldan, Claudia Rangel, Gerardo J. Alanis‐Funes, Francisco Garcia‐Sierra, Kevin Ruiz‐Fajardo, Simon Gormes‐Pinchanski, Susana Castro‐Obregón, Aranza Meza‐Dorantes, Rocio Alejandra Chavez‐Santoscoy, Isabel Arrieta‐Cruz, Paola Tristán‐Aburto, Jonathan J. Magaña, Bulmaro Cisneros   +18 more
wiley   +1 more source

La invención de los animales: una historia de la veterinaria mexicana, siglo XIX

História, Ciências, Saúde: Manguinhos, 2015
Resumen El artículo reflexiona en torno a un fenómeno que he denominado “la invención de los animales”, es decir, la manera en la que la medicina veterinaria y el ejercicio de la fisiología, la microbiología y la zootecnia produjeron un modo nuevo y ...
Blanca Irais Uribe Mendoza
doaj   +1 more source

Celebrating Rodolfo Margaria and applied physiology in Milan

Experimental Physiology, EarlyView.
Alberto E. Minetti, Gaspare Pavei, Damian M. Bailey   +2 more
wiley   +1 more source

Targeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice

Aging Cell, Volume 25, Issue 8, August 2026.
Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.
Sandra Freitas‐Rodríguez, Alejandra Valle‐Cao, Francisco Rodríguez, Manuel Fernández‐Sanjurjo, Benjamín Fernández‐García, Vanessa Loredo, María Teresa Fernández‐García, Carmen Fiuza‐Luces, Alejandro Lucia, Carlos López‐Otín, Alejandro López‐Soto, Alicia R. Folgueras   +11 more
wiley   +1 more source

Pharmacological Inhibition of Cav2.2 Channels by Recombinant Phα1β Toxin (CTK01512‐2)

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
The recombinant Phα1β toxin (CTK01512‐2) partially and reversibly inhibits Cav2.2 calcium channels in HEK‐293 cells. CTK01512‐2 displays dose‐dependent inhibition of N‐type calcium currents, with an IC50 of 3.94 nM. In vivo, CTK01512‐2 effectively reduces mechanical allodynia in a neuropathic pain model, confirming its antinociceptive activity ...
Natália Virtude Carobin, Thamyris Reis Moraes, Luana Assis Ferreira, Christopher Kushmerick, Marcus Vinícius Gomez, Célio José Castro Junior   +5 more
wiley   +1 more source

Receptores nicotínicos neuronales

Revista de la Facultad de Medicina, 2001
Desde hace varios siglos se conoce el potente efecto de la nicotina sobre los procesos cognitivos y el comportamiento. En la  actualidad, la familia de los canales iónicos activados por ligandos y particularmente los receptores nicotínicos de ...
Jaime E. Castellanos, Miguel A. Benito, René Ramírez   +2 more
doaj  

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, Volume 183, Issue 15, Page 4227-4245, August 2026.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source