Results 31 to 40 of about 10,877 (136)

Descrição atualizada da paralisia cerebral

Developmental Medicine &Child Neurology, EarlyView.
Resumo A paralisia cerebral (PC) é um termo descritivo amplamente utilizado para um espectro de deficiências motoras causadas por lesão ou malformação cerebral não progressiva ocorrida durante as fases iniciais do desenvolvimento. Avanços recentes nas áreas da genética, de pesquisa em inflamação e em neurofisiologia têm refinado a compreensão ...
Bernard Dan, Peter Rosenbaum, Lucinda Carr, Martin Gough, John Coughlan, Nonyelum Nweke   +5 more
wiley   +1 more source

CP32, a novel anti‐oomycete cyclic peptide, interferes with cell‐wall deposition in Phytophthora infestans

Journal of Integrative Plant Biology, EarlyView.
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò, Stefano Rosa, Elena Marone Fassolo, Chiara Bertaso, Andrea Tagliani, Nina Gauri Capra, Federico Ballabio, Chiara Mizzotti, Giulia Rizzi, Sadia Fida Ullah, Lisa Kappel, Lucia Feni, Luca Tadini, Louise Jane Gourlay, Rosaria Russo, Vincent Bulone, Sabrina Pricl, Sandrine Ongeri, Sara Pellegrino, Carlo Camilloni, Silvia Laura Toffolatti, Vaibhav Srivastava, Paolo Pesaresi, Simona Masiero   +23 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Transtorno disfórico pré-menstrual: um breve panorama

Debates em Psiquiatria, 2013
Enquanto muitas mulheres em idade reprodutiva sofrem em algum grau de sintomas pré-menstruais, usualmente envolvendo mudanças de humor e queixas somáticas, somente uma pequena porcentagem tem a forma mais severa, conhecida como transtorno disfórico pré ...
Renata Demarque, Joel Rennó Jr, Hewdy Lobo Ribeiro, Juliana Pires Cavalsan, Renan Rocha, Amaury Cantilino, Jerônimo de Almeida M. Ribeiro, Gislene Valadares, Antonio Geraldo da Silva   +8 more
doaj   +1 more source

Introducing OBEClust: A Pan‐European Initiative to Harmonize Obesity Prevention Research and Strengthen Translation Into Policy

Obesity Reviews, EarlyView.
ABSTRACT Obesity remains one of the most pressing public health challenges in Europe, with substantial health, social, and economic consequences. Despite extensive research and numerous national strategies, obesity prevention efforts remain fragmented across countries, limiting comparability, scalability, and policy impact.
Maria Kafyra, Pelin Alpay, Anabela Marisa Azul, Fernando Fernández‐Aranda, Sarah Forberger, Michael Georgoulis, Ioanna Panagiota Kalafati, Meropi D. Kontogianni, Thao Lam, Eirini Marouli, Paulo Matafome, Stavroula Mougiakakou, Barbara Pakula, Julio Álvarez Pitti, João Ramalho‐Santos, Katrin Scionti, Andreia Silva, Vasiliki Vavouraki, Susann Weihrauch‐Blüher, Mariusz R. Wieckowski, Manuel Tena‐Sempere, Afshan N. Malik, Dimitrios‐Dionyssios Koutsouris, Jeroen Lakerveld, Karl‐Heinz Wagner, Itziar Tueros, Philippe Froguel, Torsten Bohn, Paulo J. Oliveira, George V. Dedoussis, on behalf of OBEClust   +30 more
wiley   +1 more source

A técnica do cone para correção da anomalia de Ebstein: resultados imediatos e em longo prazo

Arquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: As principais correções da anomalia de Ebstein (AE) baseiam-se na reconstrução monocúspide da valva tricúspide e são limitadas pela frequente necessidade de substituição ou pela alta reincidência de insuficiência valvar.
José Pedro da Silva, Luciana da Fonseca da Silva, Luiz Felipe P. Moreira, Lilian Maria Lopez, Sônia Meiken Franchi, Alessandro Cavalcante Lianza, José Francisco Baumgratz, Glaucia Maria P. Tavares   +7 more
doaj  

Babesia bovis: expression of adhesion molecules in bovine umbilical endothelial cells stimulated with plasma from infected cattle

Pesquisa Veterinária Brasileira, 2014
Ten male, 12-month-old Jersey with intact spleens, serologically and parasitologically free from Babesia were housed individually in an arthropod-free isolation system from birth and throughout entire experiment.
Marlene I. Vargas, Joaquín H. Patarroyo, Mayra Hernandez, Ana P. Peconick, Adriana M. Patarroyo, Gabriel A. Tafur, Leandro S. Araújo, Fabrício Valente   +7 more
doaj   +1 more source

Effect of primary lesions in cytoskeleton proteins on red cell membrane stability in patients with hereditary spherocytosis

Frontiers in Physiology, 2022
We investigated by targeted next generation sequencing the genetic bases of hereditary spherocytosis in 25 patients and compared the molecular results with the biochemical lesion of RBC membrane obtained by SDS-PAGE analysis.
Cristina Vercellati, Anna Paola Marcello, Bruno Fattizzo, Anna Zaninoni, Agostino Seresini, Wilma Barcellini, Paola Bianchi, Elisa Fermo   +7 more
doaj   +1 more source

Trends and Approaches in Obesity and Overweight Research Focused on White Adipose Tissue and Browning: A Bibliometric Study

Obesity Reviews, EarlyView.
ABSTRACT The global rise in obesity has intensified scientific interest in adipose tissue biology, particularly the mechanisms underlying white adipose tissue (WAT) browning. This bibliometric study mapped the evolution, structure, and emerging directions of research on obesity, overweight, and WAT browning from 2011 to May 2025. Records were retrieved
Violeta Heras, Daniel Hinojosa‐Nogueira, Francisco J. Tinahones, Isabel Moreno‐Indias   +3 more
wiley   +1 more source