Results 1 to 10 of about 1,413,705 (310)
Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation
Epigenetics, 2021 Dynamic modifications of chromatin allow rapid access of the gene regulatory machinery to condensed genomic regions facilitating subsequent gene expression. Inflammatory cytokine stimulation of cells can cause rapid gene expression changes through direct
Matt J Barter +9 more
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BMC Musculoskeletal Disorders, 2021 Background Shifts in treatment strategies for rheumatoid arthritis (RA) have made ambulatory care more labour-intensive. These developments have prompted innovative care models, including mobile health (mHealth) applications.
Michaël Doumen +9 more
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STAR Protocols, 2022 Summary: Advanced techniques combining tissue clearing, deep confocal imaging, and image quantification enable researchers to characterize complex tissue architectures and understand how trauma or disease impact on their respective components.
Nicolas Peredo +5 more
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Cost-effectiveness of bringing a nurse into an Italian genetic day clinic: a before and after study
BMC Health Services Research, 2023 Background Only a few studies explore the role of nurses in genetic counselling and genetic health care, and none of them is related to orphan diseases.
Marina Mordenti +7 more
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Musclin Is Related to Insulin Resistance and Body Composition, but Not to Body Mass Index or Cardiorespiratory Capacity in Adults [PDF]
Endocrinology and Metabolism, 2021 Background We studied whether musclin function in humans is related to glycemic control, body composition, and cardiorespiratory capacity. Methods A cross-sectional study was performed in sedentary adults with or without metabolic syndrome (MS).
Yeliana L. Sánchez +11 more
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Scientific Reports, 2021 In the field of regenerative medicine, microcarriers are used as support matrix for the growth of adherent cells. They are increasingly recognised as promising biomaterials for large scale, cost-effective cell expansion bioreactor processes.
Sébastien de Bournonville +2 more
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PDGF inhibits BMP2-induced bone healing
npj Regenerative Medicine, 2023 Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling mechanisms regulating their differentiation. Using in vitro approach, we have shown that PDGF signaling through PDGFRβ inhibits BMP2-induced osteogenesis, and ...
Sanja Novak +8 more
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Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage [PDF]
, 2020 Glycogenin is considered to be an essential primer for glycogen biosynthesis. Nevertheless, patients with glycogenin-1 deficiency due to biallelic GYG1 (NM_004130.3) mutations can store glycogen in muscle.
Dellgren, Göran +10 more
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Muscle Regeneration and Function in Sports: A Focus on Vitamin D
Medicina, 2021 Muscle is one of the main targets for the biological effects of vitamin D. This hormone modulates several functions of skeletal muscles, from development to tissue repair after injury, through genomic and non-genomic mechanisms.
Giovanni Iolascon +4 more
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Rare Presentation of Sarcoidosis [PDF]
Journal of Cardio-Thoracic Medicine, 2021 Sarcoidosis is an idiopathic, noncaseating granulomatous disorder with wide systemic involvement. Lungs, eyes, and skin are the organs most commonly affected.
Suchita Pant +5 more
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