Results 31 to 40 of about 1,413,705 (310)

A personal historic perspective on the role of chloride in skeletal and cardiac muscle [PDF]

open access: yes, 2017
During the early decades of the last century, skeletal muscle was held to be impermeable to chloride ions. This theory, based on shaky grounds, was famously falsified by Boyle and Conway in 1941.
Hutter, Otto F.
core   +1 more source

Estrogen-related receptor α (ERRα) : a novel target in type 2 diabetes [PDF]

open access: yes, 2005
Recent studies have shown that reduced mitochondrial content and function in skeletal muscle are common features of type 2 diabetes. Here, we review the molecular mechanisms involved in the regulation of mitochondrial genes in skeletal muscle, focusing ...
Handschin, C., Mootha, V. K.
core   +1 more source

The effects of hibernation on the contractile and biochemical properties of skeletal muscles in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus [PDF]

open access: yes, 2013
Hibernation is a crucial strategy of winter survival used by many mammals. During hibernation, thirteen-lined ground squirrels, Ictidomys tridecemlineatus, cycle through a series of torpor bouts, each lasting more than a week, during which the animals ...
Allan   +45 more
core   +2 more sources

Implications of skeletal muscle loss for public health nutrition messages:a brief report [PDF]

open access: yes, 2015
Age-related skeletal muscle loss, sarcopenia, cachexia and wider malnutrition (under nutrition) are complex in aetiology with interaction of clinical, social and economic factors.
Levy, Louis B, Welch, Ailsa A
core   +1 more source

RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. [PDF]

open access: yes, 2020
Elevated cytoplasmic [Ca2+] is characteristic in severe skeletal and cardiac myopathies, diabetes, and neurodegeneration, and partly results from increased Ca2+ leak from sarcoplasmic reticulum stores via dysregulated ryanodine receptor (RyR) channels ...
Bers, Donald M   +6 more
core   +2 more sources

Exercise, Exerkines, and Sarcopenia [PDF]

open access: yesDiabetes & Metabolism Journal
Sarcopenia is a progressive age-related musculoskeletal disorder characterized by loss of skeletal muscle mass, strength, and physical function. Closely associated with aging and physical inactivity, it significantly compromises mobility, independence ...
Hye Soo Chung, Kyung Mook Choi
doaj   +1 more source

Mechanism reduction for multicomponent surrogates: a case study using toluene reference fuels

open access: yes, 2014
Strategies and recommendations for performing skeletal reductions of multicomponent surrogate fuels are presented, through the generation and validation of skeletal mechanisms for a three-component toluene reference fuel.
Niemeyer, Kyle E, Sung, Chih-Jen
core   +1 more source

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

open access: yes, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding   +8 more
core   +1 more source

Dietary fibre may mitigate sarcopenia risk:Findings from the NU-AGE cohort of older european adults [PDF]

open access: yes, 2020
Sarcopenia is characterised by a progressive loss of skeletal muscle mass and physical function as well as related metabolic disturbances. While fibre-rich diets can influence metabolic health outcomes, the impact on skeletal muscle mass and function is ...
Battista, Giuseppe   +14 more
core   +5 more sources

Is the Intramedullary Skeletal Kinetic Distractor a Safe Measure for Bone Lengthening? A Systematic Review

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation, 2014
Background: The intramedullary skeletal kinetic distractor (ISKD) is one of the relatively recent methods developed to overcome the complications of conventional bone lengthening methods, such as external fixators.
Ahmed Nageeb Mahmoud   +8 more
doaj   +1 more source

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