Results 11 to 20 of about 56,631 (208)

TEIDe Consortium as a model to move towards a personalized medicine approach for the prevention of cognitive impairment and dementia [PDF]

Alzheimers Dement
Abstract Dementia is a major cause of disability worldwide. Accurate identification of individuals at high risk of dementia is crucial for early diagnosis and prevention. TEIDe will examine the interplay between exercise and cognitive aging to develop practical and personalized applications in healthcare settings.
Esteban‐Cornejo I, Erickson K, Bellón J, Stensvold D, Wenger E, Possenti M, Ukropcová B, Liu‐Ambrose T.   +7 more
europepmc   +2 more sources

Enhancing access to evidence‐based dementia prevention strategies for vulnerable populations through participatory activities: A feasibility study of a multimodal lifestyle intervention (PENSA‐IMPACT) [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) disproportionately affects individuals with low socioeconomic status (SES), who face heightened risks partly due to unhealthy lifestyles and limited access to preventive care. In Spain, over 1.2 million people have dementia, with projections estimating a threefold increase by 2050.
Forcano L, Aldea A, Ayala‐García A, Cuenca‐Royo A, Gomis M, Soldevila‐Domenech N, Knezevic I, de la Torre R.   +7 more
europepmc   +2 more sources

Sex-Specific Lasting Metabolome Effects of Adverse Gestational Conditions and Prevention by Myo-Inositol Supplementation During Suckling. [PDF]

Mol Nutr Food Res
This graphical abstract illustrates the effects of myo‐inositol supplementation during suckling in reducing long‐term metabolic impacts from mild gestational calorie restriction (GCR). Using a metabolomics approach, 164 metabolites were identified, with greater metabolic alterations in males.
Martín-Chamorro RA, Martin JC, Castillo P, Palou M, Palou A, Rodríguez AM, Picó C.   +6 more
europepmc   +2 more sources

Resistance exercise for optimizing cognitive function during aging: the role of individual characteristics [PDF]

Alzheimers Dement
Abstract Physical exercise has emerged as one of the leading non‐pharmaceutical approaches to delay cognitive decline. However, the limited understanding of the mechanisms by which exercise impacts cognition and the poor description of exercise programs in late adulthood hinder the widespread use of exercise as a therapeutic or preventive approach for ...
Solis‐Urra P, Fernandez‐Gamez B, Coca‐Pulido A, Molina‐Hidalgo C, Olvera‐Rojas M, Bakker E, Bellon D, Sclafani A, Mora‐Gonzalez J, Fernandez‐Ortega J, Sánchez‐Aranda L, Martin‐Fuentes I, Toval A, Wan L, Gomez‐Rio M, Liu‐Ambrose T, Erickson K, Ortega F, Esteban‐Cornejo I.   +18 more
europepmc   +2 more sources

Metabolomic Insights Into the Impact of a Maternal Western-Style Diet and Leptin Supplementation During Suckling on Adult Rat Offspring. [PDF]

FASEB J
Plasma metabolites in adult offspring reflecting metabolic programming during critical developmental windows. ABSTRACT Perinatal nutrition influences offspring metabolic phenotype and obesity risk. This study examines how a maternal obesogenic diet and offspring's leptin supplementation during suckling affect the metabolome in offspring adulthood ...
Pomar CA, Martin-Chamorro RA, Zouhar P, Castillo P, Cajka T, Kopecky J, Palou A, Palou M, Picó C.   +8 more
europepmc   +2 more sources

The association of glycemic dysregulation with cognitive decline and structural MRI brain volumes in The Maastricht Study – A role for peripheral inflammation? [PDF]

Alzheimers Dement
Abstract Background It remains unclear whether the combination of glycemic dysregulation and peripheral inflammation is synergistically associated with accelerated cognitive decline and decreased brain volumes. Method In 2,832 persons from The Maastricht Study (N = 1,745 with longitudinal cognition measures, N = 2,523 with MRI), we assessed the ...
van Gils V, Gómez‐Martínez C, Schram M, Blokland G, Fanelli G, Bralten J, Mota N, Dalsgaard S, Jansen J, Backes W, Linden D, Wesselius A, Berendschot T, Deckers K, van der Kallen C, Koster A, van Greevenbroek M, Köhler S, Salvadó J, Visser P, Vos S, Jansen W.   +21 more
europepmc   +2 more sources

Fisiopatologia do traumatismo raquimedular. Uma revisão

Brazilian Neurosurgery, 2008
A compreensão dos mecanismos fisiopatológicos envolvidos no traumatismo raquimedular é essencial para possibilitar uma mudança no prognóstico atual do paciente com lesão medular. É apresentada, neste artigo, uma revisão dos mecanismos fisiopatológicos da
Sergio Henrique do Amaral, Marcelo Nery Silva, Marcelo Barletta Soares Viterbo, Mauricio Giraldi, Clemente Augusto de Brito Pereira   +4 more
doaj   +1 more source

Transtorno disfórico pré-menstrual: um breve panorama

Debates em Psiquiatria, 2013
Enquanto muitas mulheres em idade reprodutiva sofrem em algum grau de sintomas pré-menstruais, usualmente envolvendo mudanças de humor e queixas somáticas, somente uma pequena porcentagem tem a forma mais severa, conhecida como transtorno disfórico pré ...
Renata Demarque, Joel Rennó Jr, Hewdy Lobo Ribeiro, Juliana Pires Cavalsan, Renan Rocha, Amaury Cantilino, Jerônimo de Almeida M. Ribeiro, Gislene Valadares, Antonio Geraldo da Silva   +8 more
doaj   +1 more source

Babesia bovis: expression of adhesion molecules in bovine umbilical endothelial cells stimulated with plasma from infected cattle

Pesquisa Veterinária Brasileira, 2014
Ten male, 12-month-old Jersey with intact spleens, serologically and parasitologically free from Babesia were housed individually in an arthropod-free isolation system from birth and throughout entire experiment.
Marlene I. Vargas, Joaquín H. Patarroyo, Mayra Hernandez, Ana P. Peconick, Adriana M. Patarroyo, Gabriel A. Tafur, Leandro S. Araújo, Fabrício Valente   +7 more
doaj   +1 more source

Does Technetium-99m Diethylenetriaminepentaacetate Clearance Predict the Clinical Course of Idiopathic Pulmonary Fibrosis?

Canadian Respiratory Journal, 2004
Clearance of inhaled technetium-99m diethylenetriaminepentaacetate (99mTc-DTPA) is a potential indicator of disease activity and progression in idiopathic pulmonary fibrosis (IPF).
Marco Mura, Gelorma Belmonte, Stefano Fanti, Angela Maria Pacilli, Luca Fasano, Maurizio Zompatori, Mario Schiavina, Mario Fabbri   +7 more
doaj   +1 more source