Results 171 to 180 of about 20,584 (276)

Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui   +5 more
wiley   +1 more source

Controlling triplet-pair formation in acene-bridged trimers through locally excited-charge-transfer state mixing. [PDF]

open access: yesChem Sci
Sebastian E   +14 more
europepmc   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu   +8 more
wiley   +1 more source

Synthesis, Solubilization, and Photophysical Properties of Polyfluorinated Pentacene Dimers

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 7, July 2026.
The synthesis and photophysical analysis of polyfunctionalized pentacene dimers is described. Polyfluorination is employed to modulate the polarizability and to investigate the effects on the mechanism of singlet fission (SF). ABSTRACT A polyfluorinated pentacene dimer, linked with a 1,3‐diethynylphenylene spacer, was synthesized to investigate the ...
Zachary W. Schroeder   +10 more
wiley   +1 more source

Mass spectrometry proteomics for studying mitostasis

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma   +5 more
wiley   +1 more source

Co‐translational protein targeting to mitochondria in the context of co‐translational protein maturation

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley   +1 more source

Toward Robust ARB Inactivation in Wastewater: Comparing Performic Acid, Peracetic Acid, and Chloramination Using ICT, Resistance, and Reactivation Metrics

open access: yesWater Environment Research, Volume 98, Issue 7, July 2026.
Performic acid (PFA) achieved rapid, linear, and consistent inactivation of enterococci and vancomycin‐resistant enterococci, peracetic acid (PAA) exhibited slower, variable kinetics with distinctive shouldering, and sodium hypochlorite proved the least reliable and displayed a “lower dose advantage.” These findings position PFA as a promising ...
Nuha Alfahham   +4 more
wiley   +1 more source

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