Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
Heterocyclic biradicaloid for singlet fission: cleavage of bromine atoms from precursor 3,6-dibromo-1,4-dimethyl-piperazine-2,5-dione. [PDF]
Dron P +5 more
europepmc +1 more source
The energy dependent Pál–Bell equation and the influence of the neutron energy on the survival probability in a supercritical medium [PDF]
Eaton, MD, Saxby, JEM, Williams, MMR
core +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
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Advances in High-Temperature Irradiation-Resistant Neutron Detectors. [PDF]
Wang C, Yu R, Xia W, Gong J.
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Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
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Loess Studies in Aotearoa New Zealand
Loess in Aotearoa New Zealand (ANZ) has been studied since its first documented recognition (on Banks Peninsula) in 1878 by Julius von Haast. A decade later, John Hardcastle revealed that southern ANZ loess was both glacial in origin and contained signals of past climates.
Brent V. Alloway +4 more
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Analog Control of Reconfigurable GHz Resonances from Chiral Spin Texture Ensembles. [PDF]
Suraj TS +9 more
europepmc +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Bridging tradition and modernity: mitochondrial dynamics as a Traditional Chinese Medicine therapeutic target in cardiovascular disease. [PDF]
Du C +10 more
europepmc +1 more source

