Results 111 to 120 of about 76,221 (224)
Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong +7 more
wiley +1 more source
Global transcriptional response after exposure of fission yeast cells to ultraviolet light
Background In many cell types, including the fission yeast Schizosaccharomyces pombe, a set of checkpoints are induced by perturbations of the cell cycle or by DNA damage.
Grallert Beáta +4 more
doaj +1 more source
Cell cycle regulation of a Xenopus Wee1-like kinase [PDF]
Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner.
Coleman, Thomas R. +2 more
core
The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen +3 more
wiley +1 more source
Cell biology, SevERing mitochondria
The endoplasmic reticulum is an active participant in the division of another organelle, the ...
Lippincott-Schwarz, J., Rambold, A.
core +1 more source
Live Cell Imaging in Fission Yeast [PDF]
Live cell imaging complements the array of biochemical and molecular genetic approaches to provide a comprehensive insight into functional dependencies and molecular interactions in fission yeast. Fluorescent proteins and vital dyes reveal dynamic changes in the spatial distribution of organelles and the proteome and how each alters in response to ...
openaire +2 more sources
To Make a Long Spindle Short: Nuclear Envelope Breakdown during Meiosis
In fission yeast, the nuclear envelope (NE) remains intact during mitosis and meiosis I but is compromised during meiosis II. In this issue of Cell Reports, Flor-Parra et al.
Joseph M. Varberg, Sue L. Jaspersen
doaj +1 more source
Splitting of the fission yeast septum [PDF]
In cell-walled organisms, a cross wall (septum) is produced during cytokinesis, which then splits in certain organisms to allow the daughter cells to separate. The formation and the subsequent cleavage of the septum require wall synthesis and wall degradation, which need to be strictly coordinated in order to prevent cell lysis.
openaire +2 more sources
The fission yeast Schizosaccharomyces pombe Rec12 protein, the homolog of Spo11 in other organisms, initiates meiotic recombination by creating DNA double-strand breaks (DSBs) and becoming covalently linked to the DNA ends of the break.
Randy W Hyppa +2 more
doaj +1 more source
Pattern selection in a biomechanical model for the growth of walled cells [PDF]
In this paper, we analyse a model for the growth of three-dimensional walled cells. In this model the biomechanical expansion of the cell is coupled with the geometry of its wall. We consider that the density of building material depends on the curvature
Calvez, Vincent, Giraldi, Laetitia
core +2 more sources

