Results 91 to 100 of about 592,269 (288)

Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind cooperatively to actin and regulate myosin. [PDF]

, 2011
Tropomyosin (Tm) is an evolutionarily conserved ?-helical coiled-coil protein, dimers of which form end-to-end polymers capable of associating with and stabilising actin-filaments and regulate myosin function. The fission yeast, Schizosaccharomyces pombe,
Duncan Sousa, Mulvihill, Daniel P, East, Daniel A., Martin, Sr, Edwards, Thomas A, William Lehman, Daniel P. Mulvihill, East, Daniel A, Mulvihill, Daniel P., Sousa, Duncan, Daniel A. East, Lehman, William, Edwards, Thomas A., Thomas A. Edwards, Martin, Stephen R., Stephen R. Martin   +15 more
core   +1 more source

Adding phosphorylation events to the core oscillator driving the cell cycle of fission yeast.

PLoS ONE, 2018
Much is known about the regulatory elements controlling the cell cycle in fission yeast (Schizosaccharomyces pombe). This regulation is mainly done by the (cyclin-dependent kinase/cyclin) complex (Cdc2/Cdc13) that activates specific target genes and ...
Dania Humaidan, Frank Breinig, Volkhard Helms   +2 more
doaj   +1 more source

Role of turgor pressure in endocytosis in fission yeast

Molecular Biology of the Cell, 2014
During endocytosis, actin-dependent forces are needed to oppose internal turgor pressure for invagination of the plasma membrane. Live-cell imaging shows that addition of sorbitol to the medium significantly accelerates early steps in the endocytic ...
Roshni Basu, E. Munteanu, F. Chang
semanticscholar   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

Cytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson, Meghan E. O'Connell, Kaitlin E. Homa, Cristian Suarez, Michael L. James, Kashmeera D. Baboolall, Vilmos Zsolnay, Vladimir Sirotkin, David R. Kovar   +8 more
wiley   +1 more source

Fitness Landscape of the Fission Yeast Genome [PDF]

Molecular Biology and Evolution, 2018
Abstract Background Non-protein-coding regions of eukaryotic genomes remain poorly understood. Diversity studies, comparative genomics and biochemical outputs of genomic sites can be indicators of functional elements, but none produce fine-scale genome-wide descriptions of all functional elements.
Grech, Leanne, Jeffares, Daniel Charlton, Sadée, Christoph Yves, Rodríguez-López, María, Bitton, Danny Asher, Hoti, Mimoza, Biagosch, Carolina, Aravani, Dimitra, Speekenbrink, Maarten, Illingworth, Christopher J. R., Schiffer, Philipp H., Pidoux, Alison L., Tong, Pin, Tallada, Victor A., Allshire, Robin, Levin, Henry L., Bähler, Jürg   +16 more
openaire   +8 more sources

Conservation of the COP9/signalosome in budding yeast

BMC Genetics, 2002
Background The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal transduction, transcriptional activation, and plant ...
Susan Wee, Bettina Hetfeld, Wolfgang Dubiel, Dieter A Wolf   +3 more
doaj   +2 more sources

Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. [PDF]

PLoS ONE, 2014
Coenzyme Q (CoQ) is an essential factor for aerobic growth and oxidative phosphorylation in the electron transport system. The biosynthetic pathway for CoQ has been proposed mainly from biochemical and genetic analyses of Escherichia coli and ...
Kazuhiro Hayashi, Yuki Ogiyama, Kazumasa Yokomi, Tsuyoshi Nakagawa, Tomohiro Kaino, Makoto Kawamukai   +5 more
doaj   +1 more source

Exploring Genetic Interactions with Telomere Protection Gene pot1 in Fission Yeast

Biomolecules, 2023
The regulation of telomere length has a significant impact on cancer risk and aging in humans. Circular chromosomes are found in humans and are often unstable during mitosis, resulting in genome instability.
Masaru Ueno
doaj   +1 more source

ChIPmentation for Epigenomic Analysis in Fission Yeast. [PDF]

Methods Mol Biol
Histone modifications and transcription factor-DNA interactions regulate vital processes such as transcription, recombination, repair, and accurate chromosome segregation. Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) has been instrumental in studying genome-wide distribution of DNA-bound or chromatin-associated factors and histone ...
Dewornu FS, Tong P, Torres-Garcia S, Pidoux A, Allshire R, Shukla M.   +5 more
europepmc   +4 more sources

Mechanism of Cytokinetic Contractile Ring Constriction in Fission Yeast

Developmental Cell, 2014
SUMMARY Cytokinesis involves constriction of a contractile actomyosin ring. The mechanisms generating ring tension and setting the constriction rate remain unknown, since the organization of the ring is poorly characterized, its tension was rarely ...
M. Stachowiak, Caroline Laplante, Harvey F. Chin, Boris Guirao, E. Karatekin, T. Pollard, B. O’Shaughnessy   +6 more
semanticscholar   +1 more source