Results 81 to 90 of about 76,221 (224)
Preferential attachment in the protein network evolution
, 2003 The Saccharomyces cerevisiae protein-protein interaction map, as well as many natural and man-made networks, shares the scale-free topology. The preferential attachment model was suggested as a generic network evolution model that yields this universal ...
A. Vazquez +8 more
core +1 more source
Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4TopBP1 [PDF]
, 2013 The BRCT-domain protein Rad4(TopBP1) facilitates activation of the DNA damage checkpoint in Schizosaccharomyces pombe by physically coupling the Rad9-Rad1-Hus1 clamp, the Rad3(ATR) -Rad26(ATRIP) kinase complex, and the Crb2(53BP1) mediator.
Alcasabas +40 more
core +1 more source
The FEBS Journal, EarlyView.Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar +3 more
wiley +1 more source
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
The FEBS Journal, EarlyView.Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
Cytoplasmic microtubule organization in fission yeast [PDF]
Yeast, 2006 AbstractDuring the cell cycle of the fission yeast Schizosaccharomyces pombe, striking changes in the organization of the cytoplasmic microtubule cytoskeleton take place. These may serve as a model for understanding the different modes of microtubule organization that are often characteristic of differentiated higher eukaryotic cells.
Kenneth E, Sawin, P T, Tran
openaire +2 more sources
PLoS Biology, 2023 Mitochondria are in a constant balance of fusion and fission. Excessive fission or deficient fusion leads to mitochondrial fragmentation, causing mitochondrial dysfunction and physiological disorders.
Jiajia He +17 more
doaj +1 more source
Cell-size maintenance: universal strategy revealed
, 2015 How cells maintain a stable size has fascinated scientists since the beginning of modern biology, but has remained largely mysterious. Recently, however, the ability to analyze single bacteria in real time has provided new, important quantitative ...
Jun, Suckjoon, Taheri-Araghi, Sattar
core +2 more sources
Photochemistry and Photobiology, EarlyView.The circadian clock and melatonin coordinate homeostasis in many animals, yet their influence on reproduction and neoblast proliferation has only been shown in triclads. This study demonstrates that the early‐branching catenulid Stenostomum virginianum contains photoreceptive refractile bodies, synthesizes endogenous melatonin, and that exogenous ...
Daniel L. Stanton +5 more
wiley +1 more source
Chromatin remodeler Fft3 plays a dual role at blocked DNA replication forks
Life Science Alliance, 2019 Fft3, a member of the SNF2 family of ATPase-dependent enzymes, plays a dual role at DNA replication barriers in fission yeast by promoting both DNA resection and restart of blocked DNA replication forks. Here, we investigate the function of fission yeast
Anissia Ait-Saada +7 more
doaj +1 more source
Plants synthesize ergothioneine, showing a link to abiotic stress
Plant Biology, EarlyView.Various plants possess ergothioneine biosynthetic genes and can synthesize this antioxidant, where increased EGT levels under abiotic stress conditions indicate protective functions. Abstract Ergothioneine (EGT) is a sulphur‐containing histidine derivative and a potent antioxidant that exhibits beneficial effects on human health.
C. Kock +3 more
wiley +1 more source