Results 61 to 70 of about 592,269 (288)

Advanced Protocol for Molecular Characterization of Viral Genome in Fission Yeast (Schizosaccharomyces pombe)

Pathogens
Fission yeast, a single-cell eukaryotic organism, shares many fundamental cellular processes with higher eukaryotes, including gene transcription and regulation, cell cycle regulation, vesicular transport and membrane trafficking, and cell death ...
Jiantao Zhang, Zsigmond Benko, Chenyu Zhang, Richard Y. Zhao   +3 more
doaj   +1 more source

Improved tools for efficient mapping of fission yeast genes:identification of microtubule nucleation modifier mod22-1 as an allele of chromatin- remodelling factor gene swr1 [PDF]

, 2008
Fission yeast genes identified in genetic screens are usually cloned by transformation of mutants with plasmid libraries. However, for some genes this can be difficult, and positional cloning approaches are required.
Sawin, Kenneth E, Watt, Stephen, Bähler, Jürg, Anders, Andreas   +3 more
core   +1 more source

The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast

Molecular Biology of the Cell, 2015
The fission yeast F-BAR proteins Cdc15 and Imp2 and their combined SH3-domain partners appear to act as “molecular glue” to stabilize the interaction between the plasma membrane and a complex network of proteins at the division site that mediates cell ...
L. Ren, Alaina H. Willet, Rachel H. Roberts-Galbraith, Nathan A. McDonald, A. Feoktistova, Jun-Song Chen, Haiming Huang, Rodrigo X. Guillen, Charles Boone, S. Sidhu, Janel R Beckley, K. Gould   +11 more
semanticscholar   +1 more source

Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the pap1 transcription factor [PDF]

, 2012
Here we report the result of a genetic screen for mutants resistant to the microtubule poison methyl benzimidazol-2-yl carbamate (MBC) that were also temperature sensitive for growth.
Caroline R. Wilkinson (117644), Itaru Samejima, Mathiassen, Søs G, Penney, M., Mary Penney (117638), McInerny Christopher J., Samejima, I., Mairi Wallace (117659), Wallace Mairi, Søs G Mathiassen, Gordon Colin, Gordon, C., Wallace, Mairi, Christopher J. McInerny (117648), Hartmann-Petersen, Rasmus, Christopher J McInerny, McInerny, C.J., McInerny, Christopher J, Mary Penney, Takashi Toda (102488), Rasmus Hartmann-Petersen (117664), Toda, Takashi, Wilkinson, Caroline, Toda, T., Mathiassen Søs G., Penney, Mary, Colin Gordon, Penney Mary, Hartmann-Petersen, R., Itaru Samejima (117642), Wilkinson, C.R., Colin Gordon (117667), Hartmann-Petersen Rasmus, Søs G. Mathiassen (117654), Samejima Itaru, Wilkinson Caroline R., Mathiassen, Søs, Wilkinson, Caroline R, Rasmus Hartmann-Petersen, McInerny, Christopher, Toda Takashi, Wallace, M., Samejima, Itaru, Gordon, Colin, Takashi Toda, Mathiassen, S.G., Caroline R Wilkinson, Mairi Wallace   +47 more
core   +1 more source

Divergence of cytokinesis and dimorphism control by myosin II regulatory light chain in fission yeasts

iScience, 2023
Summary: Non-muscle myosin II activation by regulatory light chain (Rlc1Sp) phosphorylation at Ser35 is crucial for cytokinesis during respiration in the fission yeast Schizosaccharomyces pombe.
Francisco Prieto-Ruiz, Elisa Gómez-Gil, Jero Vicente-Soler, Alejandro Franco, Teresa Soto, Marisa Madrid, José Cansado   +6 more
doaj   +1 more source

A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast

Journal of Cell Biology, 2015
The formin Fus1 nucleates a novel actin structure in fission yeast, named the actin fusion focus, which consists of an aster of actin filaments whose barbed ends are focalized at a membrane proximal site and serves to focalize cell wall hydrolase ...
Omaya Dudin, Felipe Bendezú, Raphaël Groux, T. Laroche, A. Seitz, Sophie G. Martin   +5 more
semanticscholar   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

An aging-independent replicative lifespan in a symmetrically dividing eukaryote

eLife, 2017
The replicative lifespan (RLS) of a cell—defined as the number of cell divisions before death—has informed our understanding of the mechanisms of cellular aging.
Eric C Spivey, Stephen K Jones Jr, James R Rybarski, Fatema A Saifuddin, Ilya J Finkelstein   +4 more
doaj   +1 more source

The Msd1–Wdr8–Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies

Journal of Cell Biology, 2015
Msd1–Wdr8 are delivered by Pkl1 to mitotic spindle pole bodies, where the Msd1–Wdr8–Pkl1 complex anchors the minus ends of spindle microtubules and antagonizes the outward-pushing forces generated by Cut7/kinesin-5 in fission yeast.
M. Yukawa, C. Ikebe, T. Toda
semanticscholar   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source