Results 51 to 60 of about 76,221 (224)

A comparative analysis of telomere length maintenance circuits in fission and budding yeast

Frontiers in Genetics, 2022
The natural ends of the linear eukaryotic chromosomes are protected by telomeres, which also play an important role in aging and cancer development. Telomere length varies between species, but it is strictly controlled in all organisms.
Iftah Peretz, Martin Kupiec, Roded Sharan   +2 more
doaj   +1 more source

Edge usage, motifs and regulatory logic for cell cycling genetic networks

, 2013
The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solely from the ability to impose the appropriate gene expression patterns?
Krzywicki, A., Martin, O. C., Zagorski, M.   +2 more
core   +3 more sources

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion [PDF]

, 2020
Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Arrizabalaga, Gustavo, Charvat, Robert, Jacobs, Kylie   +2 more
core   +1 more source

Emerging functions of mammalian mitochondrial fusion and fission [PDF]

, 2005
Mitochondria provide a myriad of services to the cell, including energy production, calcium buffering and regulation of apoptosis. How these diverse functions are coordinated among the hundreds of mitochondria in a given cell is largely unknown, but is ...
Chan, David C., Chen, Hsiuchen
core   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Comparative Research: Regulatory Mechanisms of Ribosomal Gene Transcription in Saccharomyces cerevisiae and Schizosaccharomyces pombe

Biomolecules, 2023
Restricting ribosome biosynthesis and assembly in response to nutrient starvation is a universal phenomenon that enables cells to survive with limited intracellular resources.
Hayato Hirai, Kunihiro Ohta
doaj   +1 more source

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy [PDF]

, 2014
Development of single-molecule localization microscopy techniques has allowed nanometre scale localization accuracy inside cells, permitting the resolution of ultra-fine cell structure and the elucidation of crucial molecular mechanisms.
Adam T. Watson, Alex Herbert, Antony M. Carr, Betzig, Bähler, Culbertson, David Klenerman, David Lando, Dion, Elf, Ernest Laue, Forsburg, Heilemann, Henteges, Hess, Horrocks, Jem Tucker, Kearsey, Kim, Krichevsky, Kubota, Lando, Manley, Mark A. Osborne, Masai, Matsuyama, Matthieu Palayret, Meister, Michalet, Mortensen, Patterson, Peter Jönsson, Reyes-Lamothe, Rust, Rémi L. Boulineau, Shiomi, Sophie George, Spendier, Steven F. Lee, Stracy, Su'etsugu, Szymborska, Thomas J. Etheridge, Tokunaga, Uphoff, Watson, Yasukazu Daigaku   +46 more
core   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

FYPO: the fission yeast phenotype ontology [PDF]

Bioinformatics, 2013
Abstract Motivation: To provide consistent computable descriptions of phenotype data, PomBase is developing a formal ontology of phenotypes observed in fission yeast. Results: The fission yeast phenotype ontology (FYPO) is a modular ontology that uses several existing ontologies from the open biological and biomedical ...
Harris, Midori A, Lock, Antonia, Bähler, Jürg, Oliver, Stephen G, Wood, Valerie   +4 more
openaire   +3 more sources

Understanding the molecular mechanisms of human diseases: the benefits of fission yeasts

Microbial Cell
The role of model organisms such as yeasts in life science research is crucial. Although the baker’s yeast (Saccharomyces cerevisiae) is the most popular model among yeasts, the contribution of the fission yeasts (Schizosaccharomyces) to life science is ...
Lajos Acs-Szabo, Laszlo Attila Papp, Ida Miklos   +2 more
doaj   +1 more source