Results 51 to 60 of about 592,269 (288)
Cellular geometry scaling ensures robust division site positioning
Nature Communications, 2019 Cells divide within a given size range and can scale across differing cell sizes but mechanisms and function remain unclear. Here the authors show, despite the current dogma of fission yeast maintaining constant width, some fission yeast can scale their ...
Ying Gu, Snezhana Oliferenko
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The Multiple Functions of Rho GTPases in Fission Yeasts
Cells, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
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Basic methods for fission yeast [PDF]
Yeast, 2006 AbstractThe fission yeast Schizosaccharomyces pombe is a popular model system, and has been particularly influential in studies of the cell cycle and chromosome dynamics. Despite its differences from Saccharomyces cerevisiae, the tools and methods for fission yeast are conceptually similar to those used in budding yeast.
Susan L, Forsburg, Nicholas, Rhind
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PLoS Genetics, 2009 DNA double-strand breaks (DSBs) are formed during meiosis by the action of the topoisomerase-like Spo11/Rec12 protein, which remains covalently bound to the 5' ends of the broken DNA. Spo11/Rec12 removal is required for resection and initiation of strand
Maja Rothenberg +2 more
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Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast
Nucleic Acids Research, 2016 In budding yeast, Set2 catalyzes di- and trimethylation of H3K36 (H3K36me2 and H3K36me3) via an interaction between its Set2–Rpb1 interaction (SRI) domain and C-terminal repeats of RNA polymerase II (Pol2) phosphorylated at Ser2 and Ser5 (CTD-S2,5-P ...
Shota Suzuki +9 more
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Bub3p facilitates spindle checkpoint silencing in fission yeast [PDF]
, 2009 Although critical for spindle checkpoint signaling, the role kinetochores play in anaphase promoting complex (APC) inhibition remains unclear. Here we show that spindle checkpoint proteins are severely depleted from unattached kinetochores in fission ...
Hardwick, Kevin G. +13 more
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Functional and regulatory profiling of energy metabolism in fission yeast
Genome Biology, 2016 The control of energy metabolism is fundamental for cell growth and function and anomalies in it are implicated in complex diseases and ageing. Metabolism in yeast cells can be manipulated by supplying different carbon sources: yeast grown on glucose ...
M. Małecki +6 more
semanticscholar +1 more source
Nuclear Mechanics in the Fission Yeast [PDF]
Cells, 2019 In eukaryotic cells, the organization of the genome within the nucleus requires the nuclear envelope (NE) and its associated proteins. The nucleus is subjected to mechanical forces produced by the cytoskeleton. The physical properties of the NE and the linkage of chromatin in compacted conformation at sites of cytoskeleton contacts seem to be key for ...
Gallardo Palomo, Paola +3 more
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Phosphorylation of Arp2 is not essential for Arp2/3 complex activity in fission yeast
Life Science Alliance, 2018 This work employed genomic substitutions blocking or mimicking phosphorylation at three proposed phosphorylation sites on Arp2 to demonstrate that they do not regulate Arp2/3 complex activity in fission yeast.
Alexander E Epstein +2 more
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Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity. [PDF]
PLoS ONE, 2012 Arsenic toxicity has been studied for a long time due to its effects in humans. Although epidemiological studies have demonstrated multiple effects in human physiology, there are many open questions about the cellular targets and the mechanisms of ...
Alejandro Salgado +7 more
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