Results 31 to 40 of about 76,221 (224)
Angewandte Chemie, EarlyView.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
The Multiple Functions of Rho GTPases in Fission Yeasts
Cells, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
doaj +1 more source
Fission yeast cells grow approximately exponentially [PDF]
Cell Cycle, 2018 ABSTRACTHow the rate of cell growth is influenced by cell size is a fundamental question of cell biology. The simple model that cell growth is proportional to cell size, based on the proposition that larger cells have proportionally greater synthetic capacity than smaller cells, leads to the predication that the rate of cell growth increases ...
Mary Pickering +3 more
openaire +2 more sources
Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP*
Journal of Lipid Research, 2008 The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in ...
Adam L. Hughes +2 more
doaj +1 more source
F1000Research, 2014 Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets.
David J. Wiley +6 more
doaj +1 more source
Cellular geometry scaling ensures robust division site positioning
Nature Communications, 2019 Cells divide within a given size range and can scale across differing cell sizes but mechanisms and function remain unclear. Here the authors show, despite the current dogma of fission yeast maintaining constant width, some fission yeast can scale their ...
Ying Gu, Snezhana Oliferenko
doaj +1 more source
Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast [PDF]
, 2012 The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as ...
Allshire, Robin C +11 more
core +3 more sources
PLoS Genetics, 2009 DNA double-strand breaks (DSBs) are formed during meiosis by the action of the topoisomerase-like Spo11/Rec12 protein, which remains covalently bound to the 5' ends of the broken DNA. Spo11/Rec12 removal is required for resection and initiation of strand
Maja Rothenberg +2 more
doaj +1 more source
Phosphorylation of Arp2 is not essential for Arp2/3 complex activity in fission yeast
Life Science Alliance, 2018 This work employed genomic substitutions blocking or mimicking phosphorylation at three proposed phosphorylation sites on Arp2 to demonstrate that they do not regulate Arp2/3 complex activity in fission yeast.
Alexander E Epstein +2 more
doaj +1 more source
Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I [PDF]
, 2013 Sexually reproducing organisms halve their cellular ploidy during gametogenesis by undergoing a specialized form of cell division known as meiosis. During meiosis, a single round of DNA replication is followed by two rounds of nuclear divisions (referred
A Petrovic +40 more
core +3 more sources