Results 41 to 50 of about 592,269 (288)
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
Nature Communications, 2018 Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene expression that is critical for determining the borders between genes.
Marc Larochelle +8 more
semanticscholar +1 more source
The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast. [PDF]
, 2010 Tropomyosin (Tm) is a conserved dimeric coiled-coil protein, which forms polymers that curl around actin filaments in order to regulate actomyosin function.
Mulvihill, Daniel P. +9 more
core +1 more source
Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]
, 2014 The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Mulvihill, Daniel P. +2 more
core +1 more source
Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP*
Journal of Lipid Research, 2008 The endoplasmic reticulum membrane protein SREBP cleavage-activating protein (Scap) senses sterols and regulates activation of sterol-regulatory element binding proteins (SREBPs), membrane-bound transcription factors that control lipid homeostasis in ...
Adam L. Hughes +2 more
doaj +1 more source
Genome Research, 2016 Complex regulation of gene expression in mammals has evolved from simpler eukaryotic systems, yet the mechanistic features of this evolution remain elusive.
Gregory T. Booth +3 more
semanticscholar +1 more source
Splitting of the fission yeast septum [PDF]
FEMS Yeast Research, 2007 In cell-walled organisms, a cross wall (septum) is produced during cytokinesis, which then splits in certain organisms to allow the daughter cells to separate. The formation and the subsequent cleavage of the septum require wall synthesis and wall degradation, which need to be strictly coordinated in order to prevent cell lysis.
openaire +2 more sources
Optimization of a microarray for fission yeast [PDF]
Genomics & Informatics, 2019 Bar-code (tag) microarrays of yeast gene-deletion collections facilitate the systematic identification of genes required for growth in any condition of interest. Anti-sense strands of amplified bar-codes hybridize with ~10,000 (5,000 each for up- and down-tags) different kinds of sense-strand probes on an array.
Dong-Uk Kim +8 more
openaire +3 more sources
F1000Research, 2014 Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets.
David J. Wiley +6 more
doaj +1 more source
A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human
Cell, 2016 SUMMARY Here, we present FissionNet, a proteome-wide binary protein interactome for S. pombe, comprising 2,278 high-quality interactions, of which ~50% were previously not reported in any species.
Tommy V. Vo +19 more
semanticscholar +1 more source
RNA interference-mediated co-transcriptional gene silencing in fission yeast [PDF]
, 2012 In the last decade or so, RNA interference (RNAi) has gained unanticipated recognition in the fields of RNA biology and gene regulation. It exists in a wide variety of eukaryotic organisms, and various forms of RNAi are involved in diverse biological ...
Woolcock, Katrina Jane
core +1 more source