Results 21 to 30 of about 592,269 (288)

The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback [PDF]

, 2009
The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply
Brazma Alvis, Klier, S, Codlin, S, Lackner Daniel H., Bahler, J, Alvis Brazma, Brian T Wilhelm, Robertus A M de Bruin, Sofia Aligianni, de Bruin, RAM, Daniel H Lackner, Sandra Codlin, Gabriella Rustici, Klier Steffi, Wilhelm, BT, Rustici Gabriella, Lackner, DH, Marguerat Samuel, Aligianni, S, Bähler Jürg, de Bruin, RA, Jürg Bähler, Brazma, A, Codlin Sandra, Marguerat, S, Steffi Klier, Wilhelm Brian T., Samuel Marguerat, Aligianni Sofia, de Bruin Robertus A. M., Rustici, G   +30 more
core   +1 more source

HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe. [PDF]

PLoS ONE, 2016
BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evidence
Zsigmond Benko, Robert T Elder, Ge Li, Dong Liang, Richard Y Zhao   +4 more
doaj   +1 more source

Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis [PDF]

, 1998
The spindle checkpoint ensures proper chromosome segregation by delaying anaphase until all chromosomes are correctly attached to the mitotic spindle.
Javerzat, Jean-Paul, Javerzat, J P, Bernard, P, Hardwick, K.G., Hardwick, Kevin, Bernard, Pascal, Pascal Bernard, Jean-Paul Javerzat, Kevin Hardwick   +8 more
core   +1 more source

Reliable imaging of ATP in living budding and fission yeast

Journal of Cell Science, 2019
Adenosine triphosphate (ATP) is a main metabolite essential for all living organisms. However, our understanding of ATP dynamics within a single living cell is very limited.
Masak Takaine, Masaru Ueno, K. Kitamura, H. Imamura, S. Yoshida   +4 more
semanticscholar   +1 more source

Shaping Fission Yeast with Microtubules [PDF]

Cold Spring Harbor Perspectives in Biology, 2009
For cell morphogenesis, the cell must establish distinct spatial domains at specified locations at the cell surface. Here, we review the molecular mechanisms of cell polarity in the fission yeast Schizosaccharomyces pombe. These are simple rod-shaped cells that form cortical domains at cell tips for cell growth and at the cell middle for cytokinesis ...
Chang Fred, Martin Sophie G
openaire   +2 more sources

PomBase 2018: user-driven reimplementation of the fission yeast database provides rapid and intuitive access to diverse, interconnected information

Nucleic Acids Res., 2018
PomBase (www.pombase.org), the model organism database for the fission yeast Schizosaccharomyces pombe, has undergone a complete redevelopment, resulting in a more fully integrated, better-performing service.
A. Lock, Kim M Rutherford, M. Harris, J. Hayles, S. Oliver, J. Bähler, V. Wood   +6 more
semanticscholar   +1 more source

The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis [PDF]

, 2013
The spatial and temporal control of polarity is fundamental to the survival of all organisms. Cells define their polarity using highly conserved mechanisms that frequently rely upon the action of small GTPases, such as Ras and Cdc42.
Ladds, Graham, Wayne Croft, Bond, Michael, Croft Wayne, Cathryn Weston, Graham Ladds (430368), Graham Ladds, Cathryn Weston (471448), Croft, Wayne D., Michael Bond, Weston, Cathryn, Ladds Graham, Weston Cathryn, Bond Michael, Michael Bond (471449), Wayne Croft (471450)   +15 more
core   +1 more source

Fission yeast: in shape to divide

Current Opinion in Cell Biology, 2012
How are cell morphogenesis and cell cycle coordinated? The fission yeast is a rod-shaped unicellular organism widely used to study how a cell self-organizes in space and time. Here, we discuss recent advances in understanding how the cell acquires and maintains its regular rod shape and uses it to control cell division.
Hachet, Olivier, Bendezú, Felipe O, Martin, Sophie G   +2 more
openaire   +2 more sources

Contribution of Alanine-76 and Serine Phosphorylation in α-Synuclein Membrane Association and Aggregation in Yeasts

Parkinson's Disease, 2011
In Parkinson's disease (PD), misfolded and aggregated α-synuclein protein accumulates in degenerating midbrain dopaminergic neurons. The amino acid alanine-76 in α-synuclein and phosphorylation at serine-87 and serine-129 are thought to regulate its ...
Michael Fiske, Stephanie Valtierra, Keith Solvang, Michael Zorniak, Michael White, Sara Herrera, Alina Konnikova, Rebecca Brezinsky, Shubhik DebBurman   +8 more
doaj   +1 more source

Identification of a novel type of spacer element required for imprinting in fission yeast [PDF]

, 2011
Asymmetrical segregation of differentiated sister chromatids is thought to be important for cellular differentiation in higher eukaryotes. Similarly, in fission yeast, cellular differentiation involves the asymmetrical segregation of a chromosomal ...
Suha Sayrac, Sonya Vengrova, Dalgaard Jacob Z., Godfrey Emma L., Godfrey, Emma L., Vengrova, Sonya, Jacob Z. Dalgaard, Sayrac, Suha, Emma L Godfrey, Emma L. Godfrey, Dalgaard, Jacob Z., Jacob Z Dalgaard, Sayrac Suha, Vengrova Sonya   +13 more
core   +1 more source