Results 21 to 30 of about 34,244 (147)
The Multiple Functions of Rho GTPases in Fission Yeasts
Cells, 2021 The Rho family of GTPases represents highly conserved molecular switches involved in a plethora of physiological processes. Fission yeast Schizosaccharomyces pombe has become a fundamental model organism to study the functions of Rho GTPases over the ...
Jero Vicente-Soler +4 more
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PLoS Genetics, 2009 DNA double-strand breaks (DSBs) are formed during meiosis by the action of the topoisomerase-like Spo11/Rec12 protein, which remains covalently bound to the 5' ends of the broken DNA. Spo11/Rec12 removal is required for resection and initiation of strand
Maja Rothenberg +2 more
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F1000Research, 2014 Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks will allow identification of a greater number of therapeutic targets.
David J. Wiley +6 more
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Cellular geometry scaling ensures robust division site positioning
Nature Communications, 2019 Cells divide within a given size range and can scale across differing cell sizes but mechanisms and function remain unclear. Here the authors show, despite the current dogma of fission yeast maintaining constant width, some fission yeast can scale their ...
Ying Gu, Snezhana Oliferenko
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Phosphorylation of Arp2 is not essential for Arp2/3 complex activity in fission yeast
Life Science Alliance, 2018 This work employed genomic substitutions blocking or mimicking phosphorylation at three proposed phosphorylation sites on Arp2 to demonstrate that they do not regulate Arp2/3 complex activity in fission yeast.
Alexander E Epstein +2 more
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PathogensFission yeast, a single-cell eukaryotic organism, shares many fundamental cellular processes with higher eukaryotes, including gene transcription and regulation, cell cycle regulation, vesicular transport and membrane trafficking, and cell death ...
Jiantao Zhang +3 more
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Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity. [PDF]
PLoS ONE, 2012 Arsenic toxicity has been studied for a long time due to its effects in humans. Although epidemiological studies have demonstrated multiple effects in human physiology, there are many open questions about the cellular targets and the mechanisms of ...
Alejandro Salgado +7 more
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iScience, 2023 Summary: Non-muscle myosin II activation by regulatory light chain (Rlc1Sp) phosphorylation at Ser35 is crucial for cytokinesis during respiration in the fission yeast Schizosaccharomyces pombe.
Francisco Prieto-Ruiz +6 more
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
An aging-independent replicative lifespan in a symmetrically dividing eukaryote
eLife, 2017 The replicative lifespan (RLS) of a cell—defined as the number of cell divisions before death—has informed our understanding of the mechanisms of cellular aging.
Eric C Spivey +4 more
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