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Fission Yeast Autophagy Machinery
Autophagy is a conserved process that delivers cytoplasmic components to the vacuole/lysosome. It plays important roles in maintaining cellular homeostasis and conferring stress resistance.
Dan-Dan Xu, Li-Lin Du, Du Li-Lin
exaly +7 more sources
In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells.
Juan C. G. Cortés +4 more
doaj +5 more sources
Conserved proteins drive clathrin-mediated endocytosis (CME), which from yeast to humans involves a burst of actin assembly. To gain mechanistic insights into this process, we performed a side-by-side quantitative comparison of CME in two distantly ...
Yidi Sun +7 more
doaj +2 more sources
A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast
The CRISPR/Cas9 system, which relies on RNA‐guided DNA cleavage to induce site-specific DNA double-strand breaks, is a powerful tool for genome editing.
Xiao-Ran Zhang +3 more
doaj +2 more sources
Thermosensitivity of cellular translation restricts the growth of fission yeast at high temperatures [PDF]
Living organisms have thermal limits above which they are unable to operate and survive. Our previous genetic screen identified proteins that impede the high-temperature growth of fission yeast, including the RNA-binding protein Dri1 and a fission yeast ...
Yutaka Akikusa +10 more
doaj +2 more sources
Global analysis of fission yeast mating genes reveals new autophagy factors. [PDF]
Macroautophagy (autophagy) is crucial for cell survival during starvation and plays important roles in animal development and human diseases. Molecular understanding of autophagy has mainly come from the budding yeast Saccharomyces cerevisiae, and it ...
Ling-Ling Sun +8 more
doaj +2 more sources
A genome-wide resource of cell cycle and cell shape genes of fission yeast
To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these ...
Jacqueline Hayles +2 more
exaly +2 more sources
The natural diversity and ecology of fission yeast
Daniel C Jeffares
exaly +2 more sources
Fission Yeast Schizosaccharomyces pombe: A Unicellular “Micromammal” Model Organism
The fission yeast Schizosaccharomyces pombe is a rod‐shaped unicellular eukaryote, well known for its contributions as a model organism for our understanding of regulation and conservation of the eukaryotic cell cycle.
Aditi Vyas +3 more
semanticscholar +1 more source
3,3'-Diindolylmethane induces apoptosis and autophagy in fission yeast.
3,3'-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in the broccoli family. It induces apoptosis and autophagy in some types of human cancer. DIM extends lifespan in the fission yeast Schizosaccharomyces pombe.
Parvaneh Emami, Masaru Ueno
doaj +3 more sources

