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Fission Yeast Autophagy Machinery
Cells, 2022 Autophagy is a conserved process that delivers cytoplasmic components to the vacuole/lysosome. It plays important roles in maintaining cellular homeostasis and conferring stress resistance.
Dan-Dan Xu, Li-Lin Du
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The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis [PDF]
, 2013 The spatial and temporal control of polarity is fundamental to the survival of all organisms. Cells define their polarity using highly conserved mechanisms that frequently rely upon the action of small GTPases, such as Ras and Cdc42.
A Merla +58 more
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3,3'-Diindolylmethane induces apoptosis and autophagy in fission yeast.
PLoS ONE, 2021 3,3'-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in the broccoli family. It induces apoptosis and autophagy in some types of human cancer. DIM extends lifespan in the fission yeast Schizosaccharomyces pombe.
Parvaneh Emami, Masaru Ueno
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Cell-cycle analysis of fission yeast cells by flow cytometry. [PDF]
PLoS ONE, 2011 The cell cycle of the fission yeast, Schizosaccharomyces pombe, does not easily lend itself to analysis by flow cytometry, mainly because cells in G(1) and G(2) phase contain the same amount of DNA.
Jon Halvor Jonsrud Knutsen +5 more
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Resveratrol modulates mitochondria dynamics in replicative senescent yeast cells. [PDF]
PLoS ONE, 2014 Mitochondria form a reticulum network dynamically fuse and divide in the cell. The balance between mitochondria fusion and fission is correlated to the shape, activity and integrity of these pivotal organelles.
I-Hua Wang +5 more
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BiFCo: visualizing cohesin assembly/disassembly cycle in living cells
Life Science Alliance, 2023 A novel strategy developed in fission yeast to visualise only-assembled cohesin complex loading/unloading cycles in eukaryotic chromosomes in living cells. Cohesin is a highly conserved, ring-shaped protein complex found in all eukaryotes. It consists of
Emilio González-Martín +2 more
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Journal of Fungi, 2021 Mitogen activated protein kinase (MAPK) signaling pathways execute essential functions in eukaryotic organisms by transducing extracellular stimuli into adaptive cellular responses.
Elisa Gómez-Gil +8 more
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Bioinformatical dissection of fission yeast DNA replication origins [PDF]
Open Biology, 2020 Replication origins in eukaryotes form a base for assembly of the pre-replication complex (pre-RC), thereby serving as an initiation site of DNA replication. Characteristics of replication origin vary among species.
Koji Masuda +3 more
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Cell-cycle regulated transcription associates with DNA replication timing in yeast and human [PDF]
, 2013 Eukaryotic DNA replication follows a specific temporal program, with some genomic regions consistently replicating earlier than others, yet what determines this program is largely unknown.
Fraser, Hunter B.
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HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2016 BACKGROUND:HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and structural proteins and for maturation of infectious viral particles. Increasing evidence
Zsigmond Benko +4 more
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