Results 11 to 20 of about 34,741 (182)
Communicative & Integrative Biology, 2016 In animal cells cytokinesis relies on the contraction of an actomyosin ring that pulls the plasma membrane to create a cleavage furrow, whose ingression finally divides the mother cell into two daughter cells.
Juan C. G. Cortés +4 more
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How Fission Yeast Fission in the Middle [PDF]
Cell, 1996 In fission yeast, we propose that the division plane may be positioned by the position of the premitotic nucleus, perhaps by a signal emanating from the nucleus. Gene products involved in the assembly of the ring and its temporal and spatial controls are beginning to be characterized.
Chang, Fred, Nurse, Paul
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Nuclear Mechanics in the Fission Yeast [PDF]
Cells, 2019 In eukaryotic cells, the organization of the genome within the nucleus requires the nuclear envelope (NE) and its associated proteins. The nucleus is subjected to mechanical forces produced by the cytoskeleton. The physical properties of the NE and the linkage of chromatin in compacted conformation at sites of cytoskeleton contacts seem to be key for ...
Gallardo Palomo, Paola +3 more
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Fission yeast: in shape to divide
Current Opinion in Cell Biology, 2012 How are cell morphogenesis and cell cycle coordinated? The fission yeast is a rod-shaped unicellular organism widely used to study how a cell self-organizes in space and time. Here, we discuss recent advances in understanding how the cell acquires and maintains its regular rod shape and uses it to control cell division.
Hachet O, Bendezú FO, Martin SG
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eLife, 2019 Conserved proteins drive clathrin-mediated endocytosis (CME), which from yeast to humans involves a burst of actin assembly. To gain mechanistic insights into this process, we performed a side-by-side quantitative comparison of CME in two distantly ...
Yidi Sun +7 more
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Parkinson's Disease, 2011 In Parkinson's disease (PD), misfolded and aggregated α-synuclein protein accumulates in degenerating midbrain dopaminergic neurons. The amino acid alanine-76 in α-synuclein and phosphorylation at serine-87 and serine-129 are thought to regulate its ...
Michael Fiske +8 more
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A discrete class of intergenic DNA dictates meiotic DNA break hotspots in fission yeast.
PLoS Genetics, 2007 Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends.
Gareth A Cromie +5 more
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Shaping Fission Yeast with Microtubules [PDF]
Cold Spring Harbor Perspectives in Biology, 2009 For cell morphogenesis, the cell must establish distinct spatial domains at specified locations at the cell surface. Here, we review the molecular mechanisms of cell polarity in the fission yeast Schizosaccharomyces pombe. These are simple rod-shaped cells that form cortical domains at cell tips for cell growth and at the cell middle for cytokinesis ...
Chang Fred, Martin Sophie G
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A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast
G3: Genes, Genomes, Genetics, 2018 The CRISPR/Cas9 system, which relies on RNA‐guided DNA cleavage to induce site-specific DNA double-strand breaks, is a powerful tool for genome editing.
Xiao-Ran Zhang +3 more
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Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly [PDF]
Open Biology, 2014 CENP-A chromatin forms the foundation for kinetochore assembly. Replication-independent incorporation of CENP-A at centromeres depends on its chaperone HJURPScm3, and Mis18 in vertebrates and fission yeast.
Lakxmi Subramanian +3 more
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