Results 71 to 80 of about 34,244 (147)
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
Mitochondrial membrane remodeling in stress adaptation: Lipid control of organelle quality
Abstract Mitochondria respond to proteotoxic stress through the mitochondrial unfolded protein response, traditionally viewed as a transcriptional program that restores proteostasis by inducing chaperones and proteases. Emerging evidence indicates that mitochondrial membrane remodeling constitutes an additional adaptive component of this response ...
Lena J. Reichert +2 more
wiley +1 more source
Age‐related downregulation of AcSirt2 impairs mitochondrial homeostasis in old bees. AcSirt2‐mediated deacetylation of FOXO enhances transcriptional activity, upregulating antioxidant enzymes (SOD, CAT) and promoting PINK1/Parkin‐mediated mitophagy. This pathway facilitates autophagosome formation and clearance of damaged mitochondria, reducing ROS ...
Qiang Ma +8 more
wiley +1 more source
To Make a Long Spindle Short: Nuclear Envelope Breakdown during Meiosis
In fission yeast, the nuclear envelope (NE) remains intact during mitosis and meiosis I but is compromised during meiosis II. In this issue of Cell Reports, Flor-Parra et al.
Joseph M. Varberg, Sue L. Jaspersen
doaj +1 more source
Overview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Louise Hambücken +2 more
wiley +1 more source
Plants synthesize ergothioneine, showing a link to abiotic stress
Various plants possess ergothioneine biosynthetic genes and can synthesize this antioxidant, where increased EGT levels under abiotic stress conditions indicate protective functions. Abstract Ergothioneine (EGT) is a sulphur‐containing histidine derivative and a potent antioxidant that exhibits beneficial effects on human health.
C. Kock +3 more
wiley +1 more source
The fission yeast Schizosaccharomyces pombe Rec12 protein, the homolog of Spo11 in other organisms, initiates meiotic recombination by creating DNA double-strand breaks (DSBs) and becoming covalently linked to the DNA ends of the break.
Randy W Hyppa +2 more
doaj +1 more source
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
HP1 loses its chromatin clustering and phase separation function across evolution
Heterochromatin protein 1 (HP1) is a multifunctional chromatin-associated protein conserved from fission yeast to mammals. HP1 has been suggested to drive heterochromatin formation via phase separation.
Sanâa Bensaha +8 more
doaj +1 more source

