Results 71 to 80 of about 592,269 (288)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
In vivo movement of the type V myosin Myo52 requires dimerisation but is independent of the neck domain [PDF]
, 2007 Intracellular movement is a fundamental property of all cell types. Many organelles and molecules are actively transported throughout the cytoplasm by molecular motors, such as the dimeric type V myosins.
Mulvihill, Daniel P. +5 more
core +1 more source
Fission Yeast Cell Wall Analysis [PDF]
Cold Spring Harbor Protocols, 2017 The Schizosaccharomyces pombe cell wall is a rigid exoskeletal structure mainly composed of interlinked glucose polysaccharides and galactomannoproteins. It is essential for survival of the fission yeast, as it prevents cells from bursting from internal turgor pressure and protects them from mechanical injuries.
Pérez González, Pilar +1 more
openaire +4 more sources
A comparative analysis of telomere length maintenance circuits in fission and budding yeast
Frontiers in Genetics, 2022 The natural ends of the linear eukaryotic chromosomes are protected by telomeres, which also play an important role in aging and cancer development. Telomere length varies between species, but it is strictly controlled in all organisms.
Iftah Peretz +2 more
doaj +1 more source
Molecular Biology of the Cell, 2015 Unlike the six other Rho GEFs in fission yeast, Gef3 colocalizes with and depends on septins to localize during late cytokinesis. Gef3 binds to GDP-Rho4 and accelerates its nucleotide exchange in vitro.
Ning Wang +6 more
semanticscholar +1 more source
Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis
Advanced Science, EarlyView.In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley +1 more source
Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast [PDF]
, 2010 Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast David Walter, 2010, PhD Thesis, University of Basel Apoptosis is a form of programmed cell death that plays a central role in development and ...
Walter, David
core +1 more source
TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain
Advanced Science, EarlyView.TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando +2 more
wiley +1 more source
The Cell Biology of Fission Yeast Septation [PDF]
Microbiology and Molecular Biology Reviews, 2016 SUMMARY In animal cells, cytokinesis requires the formation of a cleavage furrow that divides the cell into two daughter cells. Furrow formation is achieved by constriction of an actomyosin ring that invaginates the plasma membrane.
Cortés, Juan Carlos G. +4 more
openaire +3 more sources
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source