Results 151 to 160 of about 592,269 (288)
Structural basis for Rap1-Rif1-Rif2 assembly : insights into budding yeast telomere architecture and functions [PDF]
Telomeres form the ends of eukaryotic linear chromosomes and are composed of specialized nucleoprotein complexes. They have been the subject of intense investigation over several decades, as telomere dysfunction has been associated with genome ...
Tianlai, Shi
core +1 more source
Overview of fission yeast septation.
This work was supported by grants BFU2013-43439-P and BIO2015-69958-P from MINECO, Spain and grant CSI037U14 from Junta de Castilla y León, Spain.
Pérez, Pilar +3 more
openaire +2 more sources
Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint [PDF]
Mitotic progression is controlled by proteolytic destruction of securin and cyclin. The mitotic E3 ubiquitin ligase, known as the anaphase promoting complex or cyclosome (APC/C), in partnership with its activators Cdc20p and Cdh1p, targets these proteins
Emma M J King +8 more
core +1 more source
Investigation of RNA-induced gene silencing in the fission yeast Schizosaccharomyces pombe
PhDRNA interference (RNAi) is a gene regulating system to which can silence genes at both transcriptional and post-transcriptional levels. In this thesis, a ura4-based RNAi selective assay was developed in the fission yeast Schizosaccharomyces pombe ...
Wang, Huan
core
This study elucidates a novel antiviral mechanism of bacterial BEVs, which are shown to inactivate viruses by triggering membrane fusion, subsequent lysis and causing structural collapse. This direct virucidal action presents a promising broad‐spectrum strategy against diverse enveloped viruses.
Yaqi Gao +15 more
wiley +1 more source
Through a screen to identify genes that induce multi-drug resistance when overexpressed, we have identified a fission yeast homolog of Int-6, a component of the human translation initiation factor eIF3.
Murray, Rachael +12 more
core +1 more source
Regulation of Meiosis in Fission Yeast.
The fission yeast Schizosaccharomyces pombe initiates sexual development under starved conditions. Nutritional starvation decreases the level of intracellular cAMP. This decrease induces expression of the ste11 gene, which encodes a key transcription factor for genes required for mating and meiosis. Mutational analyses of S.
openaire +3 more sources
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
The role of fission yeast nuclear actin-related protein in mitosis.
Nuclear actin-related proteins (Arps) have 20-30% identity to conventional actin and many are found to be in chromatin remodelling complexes. There are two families of chromatin remodelling complexes, one of which carries out covalent modification on ...
Minoda, A., Minoda, Akiko
core
Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang +12 more
wiley +1 more source

