Results 201 to 210 of about 59,495,041 (290)

Fashion Culture: From Louis Armstrong to Dizzy Gillespie: Jazz and Black Glamour

In a conversation moderated by MFIT assistant curator Elizabeth Way, historian Alphonso McClendon and vintage performer Dandy Wellington discuss the influence of jazz on 1920s fashion.

core  

'What's in a name? Fit-for-purpose bacterial nomenclature': meeting report. [PDF]

Int J Syst Evol Microbiol
Patrick S, Filkins L, Goker M, Holden N, Hoskisson PA, Kiepas A, Meehan C, Pallen M, Pritchard L, Suchanek AL, Sutcliffe I, Trujillo ME, Tucker N, Turnbull JD, Butler-Wu S.   +14 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Understanding the Neurologic and Cognitive and Behavioral Effects Associated With Exposures to Jet Fuels: A Fit-for-Purpose Systematic Literature Review. [PDF]

J Occup Environ Med
Sprowles JLN, Allen BD, Lindahl AJ, Prince LM, Bowers EC, Martin EM, Kolanowski A, Lundin M, Goodman SJ, Starnes HM, Gillera SEA, Snow SJ, Eftim SE, Haver CE, Robertson M, Vincent-Hall TD.   +15 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Are Online Maps and Booking Systems for Antenatal Vaccination Fit for Purpose? A Qualitative Study. [PDF]

Vaccines (Basel)
Tohaia P, Young A, Willing E, Fangupo L, McDonald G.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Designer Spotlight: Mariano Fortuny

The Museum at FIT presents its Designer Spotlight series where MFIT curators explore objects from our permanent collection that highlight a specific designer's work and their contributions to fashion.

core  

Understanding the Endocrine and Reproductive Health Effects Associated With Exposures to Jet Fuels: A Fit-for-Purpose Systematic Literature Review. [PDF]

J Occup Environ Med
Prince LM, Cameron RL, Jester DJ, Assefa MT, Staggs H, Adamson MM, Goodman SJ, Snow SJ, Eftim SE, Vincent-Hall TD.   +9 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source