Results 41 to 50 of about 91,473 (258)

Flatfoot diagnosis by a unique bimodal distribution of footprint index in children. [PDF]

PLoS ONE, 2014
BACKGROUND: More than 1000 scientific papers have been devoted to flatfoot issue. However, a bimodal distribution of flatfoot indices in school-aged children has never been discovered.
Chia-Hsieh Chang, Yu-Chen Chen, Wen-Tien Yang, Pei-Chi Ho, Ai-Wen Hwang, Chien-Hung Chen, Jia-Hao Chang, Liang-Wey Chang   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Assessment of Cardio Respiratory Fitness of Trained and Non-Trained Young Adult Males

Journal of Nobel Medical College, 2022
Background: Cardio respiratory fitness in terms of maximum oxygen uptake (VO2 max) reflects the physical fitness of a person. VO2max determines the capacity of an individual to perform sustained exercise.
Rekha Limbu, Nirmala Limbu, Rita Khadka, Priza Subedi, Dilmaya Limbu   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Aerobic fitness, phase angle, and bioelectrical impedance vector analysis in adolescents living with HIV: a cross-sectional study [PDF]

Revista Paulista de Pediatria
Objective: To analyze the association between phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) with aerobic fitness in HIV+ adolescents. Methods: Aerobic fitness was assessed using the modified Canadian Aerobic Fitness Test, PhA, and
Marcos Cezar Pitombo da Silva Junior, Diego Augusto Santos Silva, Priscila Custódio Martins, Nassib Bezerra Bueno, Fabiana Andréa Moura, Luiz Rodrigo Augustemak de Lima   +5 more
doaj   +1 more source

A test of the regulatory fit hypothesis in perceptual classification learning [PDF]

Memory & Cognition, 2006
This article builds a bridge between research on regulatory focus in motivation and classification learning. It tests the hypothesis that a fit between the situational regulatory focus and the reward structure of the task leads to greater cognitive flexibility than does a mismatch between situational focus and the reward structure and that the fit ...
W Todd, Maddox, Grant C, Baldwin, Arthur B, Markman   +2 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Association of Caries and Tobacco Risk with Dental Fitness Classification [PDF]

Military Medicine, 2006
Dental emergencies negatively affect the Army during combat. Dental readiness continues to be a primary mission of the Army Dental Care System and is an important part of mobilization. Dental Fitness Classification (DFC) is used to evaluate the oral health status and current treatment needs of soldiers. Caries and tobacco risk assessments were recently
Divesh, Byrappagari, Ana Karina, Mascarenhas, Jeffrey G, Chaffin   +2 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Tracking and prevalence of cardiovascular disease risk factors across socio-economic classes: A longitudinal substudy of the European Youth Heart Study

BMC Public Health, 2006
Background The highest prevalence of several cardiovascular disease risk factors including obesity, smoking and low physical activity level is observed in adults of low socioeconomic status. This study investigates whether tracking of body mass index and
Bai Charlotte N, Andersen Lars B, Møller Niels C, Wedderkopp Niels, Kristensen Peter L, Froberg Karsten   +5 more
doaj   +1 more source