Results 51 to 60 of about 15,730 (177)

Naturally Occurring ZCCHC3 Variants Modulate Antiretroviral Activity in Cynomolgus Macaques

Microbiology and Immunology, EarlyView.
ABSTRACT Many mammalian cells restrict viral replication by utilizing various host restriction factors. We recently demonstrated that CCHC‐type zinc‐finger‐containing protein 3 (ZCCHC3) suppresses human immunodeficiency virus type 1 (HIV‐1) replication through multiple mechanisms.
Jacob Fadipe, Tomotaka Okamura, Shige H. Yoshimura, Akatsuki Saito   +3 more
wiley   +1 more source

Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3

Retrovirology, 2007
We have obtained the 1.7 Å crystal structure of FIV protease (PR) in which 12 critical residues around the active site have been substituted with the structurally equivalent residues of HIV PR (12X FIV PR).
Elder John H, Torbett Bruce E, Tam Karen, Lin Ying-Chuan, Heaslet Holly, Stout C David   +5 more
doaj   +1 more source

The benefits of multidisciplinary collaboration in the successful management of two complex feline cases

Australian Veterinary Journal, EarlyView.
Despite a frequent misconception that behavioural concerns are diagnoses of exclusion, medical conditions and behavioural disorders are frequently inter‐related. In human medicine, the ‘multidisciplinary team’ approach (MDTA) is considered the most efficacious way of managing patients with complex and chronic health conditions.
BE Bollaert, JM Ley, HE Zulch
wiley   +1 more source

Prevalence of feline immunodeficiency virus and feline leukaemia virus in domestic cats in Hungary

Journal of Feline Medicine and Surgery Open Reports, 2019
Objectives Feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) are retroviruses affecting cats worldwide. The objectives of the study were to estimate the prevalence of these retroviruses in domestic cats in Hungary and to characterise ...
Anna Szilasi, Lilla Dénes, Eszter Krikó, Kristin Heenemann, Reinhard Ertl, Míra Mándoki, Thomas W Vahlenkamp, Gyula Balka   +7 more
doaj   +1 more source

Prior Puma Lentivirus Infection Modifies Early Immune Responses and Attenuates Feline Immunodeficiency Virus Infection in Cats

Viruses, 2018
We previously showed that cats that were infected with non-pathogenic Puma lentivirus (PLV) and then infected with pathogenic feline immunodeficiency virus (FIV) (co-infection with the host adapted/pathogenic virus) had delayed FIV proviral and RNA viral
Wendy S. Sprague, Ryan M. Troyer, Xin Zheng, Britta A. Wood, Martha Macmillan, Scott Carver, Susan VandeWoude   +6 more
doaj   +1 more source

Developing a Feline Immunodeficiency Virus Subtype B Vaccine Prototype Using a Recombinant MVA Vector

Vaccines, 2022
The feline immunodeficiency virus (FIV) is a retrovirus with global impact and distribution, affecting both domestic and wild cats. This virus can cause severe and progressive immunosuppression culminating in the death of felids.
Luis A. F. Andrade, Alice F. Versiani, Edel F. Barbosa-Stancioli, Jenner K. P. dos Reis, Jordana Grazziela A. C. dos Reis, Flavio G. da Fonseca   +5 more
doaj   +1 more source

Performance of point‐of‐care tests for diagnosing feline immunodeficiency virus infection in captive African lions (Panthera leo)

Australian Veterinary Journal, EarlyView.
Point‐of‐care (PoC) antibody (Ab) testing forms an integral component of feline immunodeficiency virus (FIV) diagnosis in both domestic and non‐domestic felids, with test kits designed for use in domestic cats frequently extrapolated for use in their wild counterparts. The SNAP® FIV/FeLV Combo lateral flow ELISA is commonly used to assign FIV infection
SE Jobbins, ME Westman, K Vinette Herrin, T Meili, R Hofmann‐Lehmann, JM Norris   +5 more
wiley   +1 more source

Long‐Term Outcome of Electrochemotherapy in the Treatment of Advanced Stages (T3–T4) of Feline Nasal Planum Squamous Cell Carcinoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Electrochemotherapy is increasingly used as a locoregional treatment for feline squamous cell carcinoma, but its role in advanced nasal planum disease remains poorly defined. This retrospective study evaluated the long‐term outcome of ECT as a sole treatment modality in 18 cats with T3–T4N0M0 nasal planum squamous cell carcinoma.
Delia Franchini, Ilaria Laino, Chiara Perrone, Antonio Di Bello, Stefano Ciccarelli   +4 more
wiley   +1 more source

Toxicity of Cytarabine Intravenous Constant Rate Infusion in Cats With Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Cytarabine intravenous constant rate infusion (IV CRI) toxicity in cats with lymphoma has not been well documented. We aimed to assess toxicities following cytarabine IV CRI as a single‐agent or within a multiagent protocol in cats with lymphoma. Medical records of cats with lymphoma treated with cytarabine IV CRI, with documented dose, route,
Rachel Hanford, Katherine A. Skorupski, Robert B. Rebhun, Rachel V. Brady, Sami Al‐Nadaf, Amandine T. Lejeune   +5 more
wiley   +1 more source

Aydın İlindeki Kedilerde FeLV ve FIV Enfeksiyonlarının Belirlenmesi

, 2023
 Bu çalışmanın amacı, Aydın ilinde yaşan kedilerde kedi lösemi virusu (FeLV) ve kedi immun yetmezlik virusu (FIV) varlığının belirlenmesidir. Çalışmanın materyalini; tedavi, kontrol, kastrasyon, kısırlaştırma, anti-paraziter uygulama ve aşı gibi ...
Esen, Mehmet, Aslan, Öznur
core   +1 more source