Results 91 to 100 of about 199,064 (349)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy [PDF]
, 2015 Spinal and bulbar muscular atrophy (SBMA) is characterized by loss of motoneurons and sensory neurons, accompanied by atrophy of muscle cells. SBMA is due to an androgen receptor containing a polyglutamine tract (ARpolyQ) that misfolds and aggregates ...
Aggarwal, Tanya +15 more
core +2 more sources
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Parameters Estimation of Five-phase Squirrel-Cage Induction Motor
The Transactions of the Korean Institute of Electrical Engineers, 2012 This paper propose a improved parameter estimations of five-phase squirrel-cage induction motor(IM) for speed control system on field oriented control(FOC). In order to high performance control of ac the motors using a FOC and DTC(direct torque control) algorithm, there are required precise motor parameters for slip calculation, flux observer ...
openaire +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Five-Phase Induction Motor Drive System
, 2012 Wiley Online ...
Abu-Rub, Haitham +2 more
openaire +2 more sources
A Novel Method for the Fault Diagnosis of a Planetary Gearbox based on Residual Sidebands from Modulation Signal Bispectrum Analysis [PDF]
, 2014 This paper presents a novel method for the fault diagnosis of planetary gearboxes based on an accurate estimation of residual sidebands using a modulation signal bispectrum (MSB).
Abdalla, Gaballa M. +4 more
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Solar array fed synchronous reluctance motor driven water pump : an improved performance under partial shading conditions [PDF]
, 2019 An improved performance of a photovoltaic (PV) pumping system employing a synchronous reluctance motor (SynRM) under partial shading conditions is proposed.
Al-Dhaifallah, Mujahed +3 more
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source