Results 91 to 100 of about 51,959 (304)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Fast Method for the Iron Losses Prediction in Inverter Fed Induction Motors [PDF]

open access: yes, 2009
In this paper an easy method for the iron loss prediction in PWM inverter fed induction motors is presented. The method was initially proposed and validated for the prediction of the iron losses in non-oriented soft magnetic material with PWM supply ...
A. Boglietti   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Neural Network-Based Model Reference Adaptive System for Torque Ripple Reduction in Sensorless Poly Phase Induction Motor Drive

open access: yesEnergies, 2019
This paper proposes the modified, extended Kalman filter, neural network-based model reference adaptive system and the modified observer technique to estimate the speed of a five-phase induction motor for sensorless drive.
S. Usha   +2 more
doaj   +1 more source

Basic Comparison and Evaluation of Functionality AC-AC Matrix Converter Concepts for HEV Vehicle - Part II

open access: yesCommunications, 2020
The paper deals with a modeling and simulation of the direct AC-AC propulsion system and compares two matrix converter concepts with five-phase traction induction motors (IM) for the hybrid electric vehicle (HEV).
Branislav Dobrucky   +3 more
doaj   +1 more source

Five-Phase Induction Motor Drive System

open access: yes, 2012
Wiley Online ...
Abu-Rub, Haitham   +2 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Vectorial Approach Based Control of a Seven-Phase Axial Flux Machine Designed for Fault Operation [PDF]

open access: yes, 2008
Version éditeur disponible à l'adresse suivante : http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4519973&isnumber=4636792This paper deals with easy-to-implement control strategies when a seven-phase axial flux permanent magnet machine supplied ...
LOCMENT, Fabrice   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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