Results 31 to 40 of about 2,484 (267)

Fault Tolerant Control of Five-Level Inverter Based on Redundancy Space Vector Optimization and Topology Reconfigruation

IEEE Access, 2020
Compared with two-level and three-level inverters, five-level inverters have more redundant space vectors to implement flexible control strategy. A fault tolerance method for open circuit fault of power tube in Neutral Point Clamped (NPC) five level ...
Yunjun Yu, Xiaoming Li, Lili Wei
doaj   +1 more source

Performance investigations of five-level reduced switches count Η-bridge multilevel inverter

Electrical engineering & Electromechanics, 2023
Introduction. This research paper describes a simple five-level single-phase pulse-width modulated inverter topology for photovoltaic grid applications. Multilevel inverters, as opposed to conventional two-level inverters, include more than two levels of
E. Parimalasundar, S. Muthukaruppasamy, R. Dharmaprakash, K. Suresh   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A five‐level nested neutral point‐clamped inverter topology

IET Power Electronics
Classical five‐level nested neutral point‐clamped (5L NNPC) inverter‐leg is a hybrid of the flying‐capacitor and diode‐clamped 5‐L inverter‐leg configurations.
Desmond O. Obe, Chinedu T. Obe, Charles I. Odeh, Emeka S. Obe   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Investigation of Highly Efficient Five Level Asymmetrical Inverter Family With Embedded Buck-Boost Converter

IEEE Access, 2022
In recent years, focus is given to the increment of the power conversion efficiency of multilevel inverters with integrated voltage boosting characteristics.
Theodoros P. Mouselinos, Emmanuel C. Tatakis   +1 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A Single-Phase Five-Level Switched-Capacitor Boost Inverter With Improving Voltage Gain

IEEE Access
In this paper, a new topology of single-phase five-level switched-capacitor boost inverter (5L-SCBI) is introduced to improve voltage gain in comparison with existing impedance-source inverters (ISIs).
Duc-Tri Do, Thuan-Thien Vu, Khai M. Nguyen, Vinh-Thanh Tran   +3 more
doaj   +1 more source