Results 41 to 50 of about 12,841,457 (249)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Five-level F-type inverter with buck-boost converter-based equalization channels

Alexandria Engineering Journal, 2023
Multilevel inverters have been widely used in various applications, as they provide output voltage with better quality, lower dv/dt, and lower Total Harmonic Distortion (THD).
Ahmed A. Elserougi, Ibrahim Abdelsalam, Ahmed Massoud   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

A Simple Strategy of Controlling a Balanced Voltage Capacitor in Single Phase Five-Level Inverter [PDF]

, 2015
The five-level inverter has been used for many applications in renewable energy systems. Even though its harmonic distortion was lower than the conventional two-level inverter.
Eka Firmansyah, F. Danang Wijaya, Wijaya, F. Danang, Pratomo, Leonardus Heru, Firmansyah, Eka, Leonardus Heru Pratomo   +5 more
core   +2 more sources

A Different Voltage-Source Power Inverter with Carrier Based SPWM for Open-End Connection Loads

Energies, 2019
This paper presents a new configuration of voltage source inverter with a simplified circuit for generating five-level pulse width modulation (PWM) voltage waveform.
Suroso, Daru Tri Nugroho, Toshihiko Noguchi   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Fault Tolerant Control of Five-Level Inverter Based on Redundancy Space Vector Optimization and Topology Reconfigruation

IEEE Access, 2020
Compared with two-level and three-level inverters, five-level inverters have more redundant space vectors to implement flexible control strategy. A fault tolerance method for open circuit fault of power tube in Neutral Point Clamped (NPC) five level ...
Yunjun Yu, Xiaoming Li, Lili Wei
doaj   +1 more source

Simplified space vector PWM algorithm for five-level inverter

, 2007
In this work, we present an algorithm for the space vector pulse width modulation (SVPWM) applied to five-level diode clamped inverter. In this algorithm, the space vector diagram of the five-level inverter is decomposed into six space vector diagrams
D. Lalili, J. Petzold, F. Boudjema, E. M. Berkouk, N. Lourci, T. Taleb   +5 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

A five‐level nested neutral point‐clamped inverter topology

IET Power Electronics
Classical five‐level nested neutral point‐clamped (5L NNPC) inverter‐leg is a hybrid of the flying‐capacitor and diode‐clamped 5‐L inverter‐leg configurations.
Desmond O. Obe, Chinedu T. Obe, Charles I. Odeh, Emeka S. Obe   +3 more
doaj   +1 more source