Results 51 to 60 of about 10,829,109 (259)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Generalized Model Predictive Control Algorithm for a Five-Phase Induction Motor

Algorithms
This paper proposes a Generalized Predictive Control (GPC) approach for the inner current-control loop of a multiphase induction motor drive. The method is based on a CARIMA model, which inherently provides integral action, allowing steady-state error ...
Antonio J. Gallego, Juana M. Martínez-Heredia, Pablo Velarde   +2 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Fault Diagnosis of Induction Motor Based on a Novel Intelligent Framework and Transient Current Signals [PDF]

, 2013
This paper deals with fault diagnosis of induction motor containing common faults by using a novel intelligent framework and transient stator current signals. This framework consists of a Fourier-Bessel (FB) expansion for analyzing the transient signals,
Tran, V.T., Ball, Andrew, Liang, Bo, Cattley, R., Tran, Van Tung, Ball, A., Cattley, Robert, Iwnicki, S., Iwnicki, Simon   +8 more
core   +1 more source

Reduction of common-mode voltage using a simplified FSC-MPC for a five-phase induction motor drive

The Journal of Engineering, 2019
This paper presents a cascaded closed-loop control of a five-phase induction motor (IM) drive system with common-mode voltage reduction capability. The outer loop uses standard PI regulators for speed reference tracking, while the inner control loop is ...
Hugo Guzman, Atif Iqbal, Federico Barrero, Federico Barrero   +3 more
doaj   +1 more source

A Novel Sensorless Control for Multiphase Induction Motor Drives Based on Singularly Perturbed Sliding Mode Observer-Experimental Validation

Applied Sciences, 2020
This paper aims to develop an innovative sensorless control approach for a five-phase induction motor (IM) drive. The operation principle of the sensorless scheme is based on the sliding mode theory, within which a sliding mode observer (SMO) estimates ...
Mahmoud A. Mossa, Hamdi Echeikh, Atif Iqbal, Ton Duc Do, Ameena Saad Al-Sumaiti   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Investigation on SVM-Backstepping sensorless control of five-phase open-end winding induction motor based on model reference adaptive system and parameter estimation

Engineering Science and Technology, an International Journal, 2019
This paper deals with a new control technique applied to five-phase induction motor under open-end stator winding (FPIM-OESW) topology using the backstepping nonlinear control.
Khadar Saad, Kouzou Abdellah, Hafaifa Ahmed, Atif Iqbal   +3 more
doaj   +1 more source

Modified SPWM Technique with Zero-Sequence Voltage Injection for a Five-Phase, Three-Level NPC Inverter

Energies, 2021
This article presents a modified sinusoidal pulse-width modulation (SPWM) scheme for a five-phase, three-level neutral-point-clamped inverter. The modulation scheme deploys a modified min–max function to inject the zero-sequence components into the ...
Charles Odeh, Dmytro Kondratenko, Arkadiusz Lewicki, Andrzej Jąderko   +3 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source