Results 111 to 120 of about 317,820 (317)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Drosophila yakuba mayottensis, a new model for the study of incipient ecological speciation

open access: yesFly, 2017
A full understanding of how ecological factors drive the fixation of genetic changes during speciation is obscured by the lack of appropriate models with clear natural history and powerful genetic toolkits.
Amir Yassin
doaj   +1 more source

X Chromatin inactivation in Menopause: A study on Hindu caste Bengalee population

open access: yesAsian Journal of Medical Sciences, 2018
Background: Menopause being a physiologic event and eventually the prime time to perform risk assessment of chronic diseases and initiate preventive health measures. Previous studies reported, later menopause is independently associated to increased risk
Koel Mukherjee   +2 more
doaj   +1 more source

Population Genetic Diversity of Two Marine Gobies (Gobiiformes: Gobiidae) from the North-Eastern Atlantic and the Mediterranean Sea

open access: yesJournal of Marine Science and Engineering, 2020
Gobies (Gobiiformes: Gobiidae) are the most species-rich family of fishes in general, and the most abundant fish group in the European seas. Nonetheless, our knowledge on many aspects of their biology, including the population genetic diversity, is poor.
Katarína Čekovská   +7 more
doaj   +1 more source

Genetic relatedness of previously Plant-Variety-Protected commercial maize inbreds. [PDF]

open access: yesPLoS ONE, 2017
The emergence of high-throughput, high-density genotyping methods combined with increasingly powerful computing systems has created opportunities to further discover and exploit the genes controlling agronomic performance in elite maize breeding ...
Travis J Beckett   +3 more
doaj   +1 more source

Stochastic tunneling and metastable states during the somatic evolution of cancer

open access: yes, 2015
Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential acquisition of (epi)genetic alterations has been the topic of much ...
Ashcroft, Peter   +2 more
core   +1 more source

Differentiation measures for conservation genetics

open access: yesEvolutionary Applications, 2018
We compare the two main classes of measures of population structure in genetics: (i) fixation measures such as FST, GST, and θ and (ii) allelic differentiation measures such as Jost's D and entropy differentiation.
L. Jost   +5 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Genetic diversity and population genetic structure analysis of Echinococcus granulosus sensu stricto complex based on mitochondrial DNA signature. [PDF]

open access: yesPLoS ONE, 2013
The genetic diversity and population genetics of the Echinococcus granulosus sensu stricto complex were investigated based on sequencing of mitochondrial DNA (mtDNA).
Monika Sharma   +5 more
doaj   +1 more source

Population genetics of fungal and oomycete effectors involved in gene-for-gene interactions.

open access: yesMolecular Plant-Microbe Interactions, 2009
Antagonistic coevolution between plants and pathogens has generated a broad array of attack and defense mechanisms. In the classical avirulence (Avr) gene-for-gene model, the pathogen gene evolves to escape host recognition while the host resistance (R ...
E. Stukenbrock, B. McDonald
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy