Results 111 to 120 of about 5,625,610 (302)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Population genetics, behavioural ecology and management of the Greywing Francolin Francolinus africanus [PDF]

open access: yes, 1992
Bibliography: p. 237-249.This study investigates the population genetics and behavioural ecology of the Greywing Francolin, Francolinus africanus, and identifies factors which influence the distribution and abundance of this important gamebird.
Little, Rob M
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations

open access: yesForensic Sciences Research, 2020
Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method.
Yijie Wang   +8 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Population Genetics of the Invasive Red Fox, Vulpes vulpes, in South-Eastern Australia

open access: yes, 2021
The use of genetic information in conservation biology has become more widespread with genetic information more readily available for non-model organisms.
Katarina M. Mikac   +2 more
core   +1 more source

Genetic diversity of toll-like receptor genes in the vulnerable Chinese egret (Egretta eulophotes).

open access: yesPLoS ONE, 2020
Toll-like receptor (TLR) genes have recently been employed to assess genetic diversity, as they can be used to infer both demographic history and adaptation to environments with different pathogen pressure. Here, we sampled 120 individuals of the Chinese
Wei Xu   +3 more
doaj   +1 more source

Differentiation measures for conservation genetics

open access: yesEvolutionary Applications, 2018
We compare the two main classes of measures of population structure in genetics: (i) fixation measures such as FST, GST, and θ and (ii) allelic differentiation measures such as Jost's D and entropy differentiation.
L. Jost   +5 more
semanticscholar   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Population genetics of fungal and oomycete effectors involved in gene-for-gene interactions.

open access: yesMolecular Plant-Microbe Interactions, 2009
Antagonistic coevolution between plants and pathogens has generated a broad array of attack and defense mechanisms. In the classical avirulence (Avr) gene-for-gene model, the pathogen gene evolves to escape host recognition while the host resistance (R ...
E. Stukenbrock, B. McDonald
semanticscholar   +1 more source

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