This study provides the first definitive identification of tunnelling nanotubes (TNTs) between cultured osteocytes and shows TNT‐mediated lysosome transfer from healthy to stressed cells, restoring autophagic flux and preventing apoptosis. This discovery of transcellular autophagy reveals a new survival mechanism in osteocytes, offering potential ...
Jinbiao Qiang +16 more
wiley +1 more source
Effect of Surgical Specimen Chain Management Information System on specimen management in operating room: a pilot Quasi-Experimental study. [PDF]
Zhang X +6 more
europepmc +1 more source
Scatter plots from all cases were categorized into four plot types. Cytologically negative cases mainly exhibited Small cluster (S‐type) and Horizontal (H‐type) patterns, whereas cytologically positive cases predominantly showed Vertical (V‐type) and Diagonal (D‐type) patterns.
Rio Kaneko +7 more
wiley +1 more source
Optimizing chromosome dispersion quality: the key role of cell density. [PDF]
Gao CX +6 more
europepmc +1 more source
Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono +3 more
wiley +1 more source
Long-term fixation impact on archived human nervous tissues for sequencing-based transcriptomics. [PDF]
Howe S +6 more
europepmc +1 more source
Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney +10 more
wiley +1 more source
Assessing the limitations of paraformaldehyde fixation for accurate cell surface receptor measurement. [PDF]
Bernard E +4 more
europepmc +1 more source
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam +4 more
wiley +1 more source
In Situ Analysis of Historical Preservation Fluids in Sealed Containers with Spatially Offset Raman Spectroscopy. [PDF]
Blanco A +6 more
europepmc +1 more source

