Results 291 to 300 of about 158,082 (381)

Quantitative T1 is sensitive to cortical remyelination in multiple sclerosis: A postmortem MRI study

Brain Pathology, EarlyView.
In a post‐mortem study using multiparametric qMRI of whole fixed human brains from people with multiple sclerosis (pwMS), we found evidence that quantitative T1 (qT1) is sensitive to remyelination in the cortex. In contrast, QSM and radial diffusivity were affected by cortical pathology independently of remyelination. Our data suggest that qT1 could be
Riccardo Galbusera, Matthias Weigel, Erik Bahn, Sabine Schaedelin, Alessandro Cagol, Po‐Jui Lu, Muhamed Barakovic, Lester Melie‐Garcia, Jonas Franz, Peter Dechent, Govind Nair, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera   +14 more
wiley   +1 more source

Pigment granule architecture varies across yellow, red, and brown chromatophores in squid Doryteuthis pealeii. [PDF]

Sci Rep
Bower DQ, Senft SL, Hanlon RT, Deravi LF.   +3 more
europepmc   +1 more source

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić, Petra Šoštarić, Davor Virag, Ana Knezović, Nikola Habek, Ornella Rossetto, Ivica Matak   +6 more
wiley   +1 more source

A rosin-functionalized plastic surface inactivates African swine fever virus. [PDF]

Front Vet Sci
Hemmink JD, Shroff S, Chege N, Haapakoski M, Dixon LK, Marjomäki V.   +5 more
europepmc   +1 more source

Dopamine D3 receptor blockade accelerates the extinction of opioid withdrawal‐induced drug‐seeking behaviours and alters microglia in dopaminoceptive nuclei

British Journal of Pharmacology, EarlyView.
Background and Purpose Among all drugs of abuse, opioids cause most of the deaths and treatment seeking. Despite abundant research in multifaceted therapeutic strategies, a high rate of relapse still characterises this condition. Dopamine D3 receptor antagonists combined with cue‐exposure therapies have been proposed to ameliorate the abused drugs ...
Aurelio Franco‐García, Victoria Gómez‐Murcia, M. Victoria Milanés, Cristina Núñez   +3 more
wiley   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

Cell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li, Jingya Zhang, Xu Wang, Xinru Wang, Yuyu Song, Xinyue Song, Xiuli Wang, Weiwei Cao, Chong Zhao, Jing Qi, Xiaodong Zheng, Yan Xing   +11 more
wiley   +1 more source

Comparative analysis of fixation techniques for signal detection in avian embryos. [PDF]

Dev Biol
Echeverria CV, Leathers TA, Rogers CD.
europepmc   +1 more source

tRF‐3a‐Pro: A Transfer RNA‐Derived Small RNA as a Novel Biomarker for Diagnosis of Hepatitis B Virus‐Related Hepatocellular Carcinoma

Cell Proliferation, EarlyView.
tRF‐3a is the main tsRNA subtype up‐regulated in HBV‐related HCC. tRF‐3a‐Pro is significantly up‐regulated in HBV‐related HCC tumour than that in paratumour tissues. The level of tRF‐3a‐Pro in serum is a promising candidate biomarker for HCC diagnosis. tRF‐3a‐Pro promotes cell proliferation and regulates cell cycle of HCC.
Jingyi Si, Yanting Zou, Yifan Gao, Jia Chen, Wei Jiang, Xizhong Shen, Changfeng Zhu, Qunyan Yao   +7 more
wiley   +1 more source

Chromosomes of four species of dobsonflies, in the genus <i>Protohermes</i> (Megaloptera, Corydalidae, Corydalinae) from East Asia. [PDF]

Comp Cytogenet
Takeuchi Y, Iizuka K, Koishi H, Hoshiba H.   +3 more
europepmc   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source