Results 51 to 60 of about 146,660 (246)

Preservation Methods Differ in Fecal Microbiome Stability, Affecting Suitability for Field Studies. [PDF]

, 2016
Immediate freezing at -20°C or below has been considered the gold standard for microbiome preservation, yet this approach is not feasible for many field studies, ranging from anthropology to wildlife conservation.
Amnon Amir, Greg Humphrey, Jessica L. Metcalf, Katherine R. Amato, M. Denise Dearing, Rob Knight, Se Jin Song, Zhenjiang Zech Xu   +7 more
core   +2 more sources

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Neuronal processing of translational optic flow in the visual system of the shore crab Carcinus maenas [PDF]

, 2011
This paper describes a search for neurones sensitive to optic flow in the visual system of the shore crab Carcinus maenas using a procedure developed from that of Krapp and Hengstenberg.
Bachmann, Barnes, Barnes, Barnes, Barnes, Barnes, Batschelet, Berón de Astrada, Berón de Astrada, Berón de Astrada, Blanke, Bremmer, Bush, Collett, Copello, Dacke, Dahmen, David, Eckert, Esch, Farina, Gibson, Gibson, Gibson, Glantz, Glantz, Glantz, Green, Götz, Haag, Haag, Hassenstein, Hausen, Hausen, Hausen, Hausen, Hemmi, Hemmi, Holmqvist, Horridge, Horridge, Hyslop, Johnson, Karmeier, Kern, Kern, Kirk, Kirk, Koenderink, Krapp, Krapp, Krapp, Krapp, Krapp, Land, Land, Land, Layne, Layne, Layne, Layne, Layne, Layne, Lindemann, Medan, Merkle, Nilsson, Oliva, Paolini, Paul, Paul, Pearson, Pfeiffer, Ronacher, Saito, Shafir, Simpson, Srinivasan, Srinivasan, Srinivasan, Stewart, Strausfeld, Sun, Sztarker, Sztarker, Sztarker, Tammero, Tanaka, Taylor, Tomsic, van den Berg, Wagner, Walls, Walls, Wang, Waterman, Wicklein, Wiersma, Wiersma, Wiersma, Wiersma, Wittlinger, Wittlinger, Wylie, York, Zeil, Zeil, Zeil   +107 more
core   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source

Kennedy Space Center Fixation Tube (KFT) [PDF]

Experiments performed on the International Space Station (ISS) frequently require the experimental organisms to be preserved until they can be returned to earth for analysis in the appropriate laboratory facility.
Levine, Howard G., Richards, Stephanie E., Romero, Vergel   +2 more
core   +1 more source

To the knowledge of the genus Pseudospora Cienkowski [Translation from: Archiv fur Protistenkunde 59, 350-368, 1927] [PDF]

, 1981
Morphological observations on the two types of Pseudospora are given. The two Pseudospora whic are described are Pseudospora eudorini and Pseudospora volvocis.
Roskin, G.
core  

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Functional preservation of vascular smooth muscle tissue [PDF]

The ionic and cellular feedback relationships operating to effect the vascular decompensatory modifications were examined to reveal procedures for implementing protective measures guarding against vascular collapse when returning from a weightless ...
Alexander, W. C., Hutchins, P. M., Kimzey, S. L.   +2 more
core   +1 more source

Interaction of hypothalamic GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors controlling heart rate in rats [PDF]

, 1991
We have previously shown that microinjection of drugs that impair gamma-aminobutyric acid (GABA)-mediated synaptic inhibition into the dorsomedial hypothalamus (DMH) of rats generates cardiovascular and behavioral changes that mimic the response to ...
DiMicco, Joseph A., Soltis, Robert P.
core   +2 more sources

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source